A Single Fungal Strain Was the Unexpected Cause of a Mass Aspergillosis Outbreak in the World’s Largest and Only Flightless Parrot

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aut.relation.articlenumber105470
aut.relation.issue12
aut.relation.journaliScience
aut.relation.startpage105470
aut.relation.volume25
dc.contributor.authorWinter, DJ
dc.contributor.authorWeir, BS
dc.contributor.authorGlare, T
dc.contributor.authorRhodes, J
dc.contributor.authorPerrott, J
dc.contributor.authorFisher, MC
dc.contributor.authorStajich, JE
dc.contributor.authorDigby, A
dc.contributor.authorDearden, PK
dc.contributor.authorCox, MP
dc.date.accessioned2023-08-02T02:22:12Z
dc.date.available2023-08-02T02:22:12Z
dc.date.issued2022-11-02
dc.description.abstractKākāpō are a critically endangered species of parrots restricted to a few islands off the coast of New Zealand. Kākāpō are very closely monitored, especially during nesting seasons. In 2019, during a highly successful nesting season, an outbreak of aspergillosis affected 21 individuals and led to the deaths of 9, leaving a population of only 211 kākāpō. In monitoring this outbreak, cultures of aspergillus were grown, and genome sequenced. These sequences demonstrate that, very unusually for an aspergillus outbreak, a single strain of aspergillus caused the outbreak. This strain was found on two islands, but only one had an outbreak of aspergillosis; indicating that the strain was necessary, but not sufficient, to cause disease. Our analysis provides an understanding of the 2019 outbreak and provides potential ways to manage such events in the future.
dc.identifier.citationiScience, ISSN: 2589-0042 (Print); 2589-0042 (Online), Elsevier BV, 25(12), 105470-. doi: 10.1016/j.isci.2022.105470
dc.identifier.doi10.1016/j.isci.2022.105470
dc.identifier.issn2589-0042
dc.identifier.issn2589-0042
dc.identifier.urihttp://hdl.handle.net/10292/16497
dc.languageeng
dc.publisherElsevier BV
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S2589004222017424
dc.rights© 2022 The Author(s). This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)
dc.rights.accessrightsOpenAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectAnimals
dc.subjectMicrobiology
dc.subjectMicrobiology parasite
dc.subjectParasitology
dc.subjectKākāpō Aspergillosis Research Consortium
dc.subject3107 Microbiology
dc.subject31 Biological Sciences
dc.subjectEmerging Infectious Diseases
dc.subjectRare Diseases
dc.subjectInfectious Diseases
dc.subjectInfection
dc.titleA Single Fungal Strain Was the Unexpected Cause of a Mass Aspergillosis Outbreak in the World’s Largest and Only Flightless Parrot
dc.typeJournal Article
pubs.elements-id483541
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