Prediabetes is Pre-Nothing: Call It Early Type 2 Diabetes [Editorial]
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AOSIS
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Prediabetes is often a footnote in primary care, flagged inconsistently on lab reports, mentioned briefly or ignored for ‘watchful waiting’. This passive approach fails to reflect the biological reality. Long before HbA1c reaches the diagnostic threshold for type 2 diabetes (T2D) (≥48 mmol/mol or ≥6.5%), the disease process is active: insulin resistance, hyperinsulinaemia and β-cell stress drive early microvascular and cardiovascular damage.
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Journal of Metabolic Health. 2025;8(1), a132. ISSN: (Online) 2960-0391, (Print) 3105-4323
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© 2025. The Author. Licensee: AOSIS. This work is licensed under the Creative Commons Attribution 4.0 International (CC BY 4.0) license (https://creativecommons.org/licenses/by/4.0/)