One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with MS
aut.relation.issue | 109 | |
aut.relation.volume | 14 | |
aut.researcher | Kersten, Paula | |
dc.contributor.author | Thomas, P | |
dc.contributor.author | Thomas, S | |
dc.contributor.author | Kersten, P | |
dc.contributor.author | Jones, R | |
dc.contributor.author | Slingsby, V | |
dc.contributor.author | Nock, A | |
dc.contributor.author | Davies Smith, A | |
dc.contributor.author | Baker, R | |
dc.contributor.author | Galvin, K | |
dc.contributor.author | Hillier, C | |
dc.date.accessioned | 2015-01-12T02:59:04Z | |
dc.date.available | 2015-01-12T02:59:04Z | |
dc.date.copyright | 2014 | |
dc.date.issued | 2014 | |
dc.description.abstract | Background Fatigue is one of the most common and debilitating symptoms of multiple sclerosis (MS). The aim was to evaluate the effectiveness at 1-year follow-up of a manualised group-based programme (‘FACETS’) for managing MS-fatigue. Methods One-year follow-up of a pragmatic multi-centre randomised controlled trial. People with MS and significant fatigue were randomised to FACETS plus current local practice (FACETS) or current local practice alone (CLP), using concealed computer-generated randomisation. Participant blinding was not possible. Primary outcome measures were fatigue severity (Global Fatigue Severity subscale of the Fatigue Assessment Instrument), self-efficacy (MS-Fatigue Self-Efficacy) and disease-specific quality of life (MS Impact Scale). Results Between May 2008 and November 2009, 164 participants were randomised. Primary outcome data were available at 1 year for 131 (80%). The benefits demonstrated at 4-months in the FACETS arm for fatigue severity and self-efficacy largely persisted, with a slight reduction in standardised effect sizes (SES) (−0.29, p = 0.06 and 0.34, p = 0.09, respectively). There was a significant difference on the MS Impact Scale favouring FACETS that had not been present at 4-months (SES −0.24, p = 0.046). No adverse events were reported. Conclusions Improvements in fatigue severity and self-efficacy at 4-months follow-up following attendance of FACETS were mostly sustained at 1 year with additional improvements in MS impact. The FACETS programme provides modest long-term benefits to people with MS-fatigue. | |
dc.identifier.citation | BMC Neurology 2014, 14:109 doi:10.1186/1471-2377-14-109 | |
dc.identifier.doi | 10.1186/1471-2377-14-109 | |
dc.identifier.uri | https://hdl.handle.net/10292/8279 | |
dc.publisher | BioMed Central | |
dc.relation.uri | http://dx.doi.org/10.1186/1471-2377-14-109 | |
dc.rights | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | |
dc.rights.accessrights | OpenAccess | |
dc.subject | Randomised controlled trial | |
dc.subject | Multiple sclerosis | |
dc.subject | Fatigue | |
dc.subject | Intervention | |
dc.subject | Energy effectiveness | |
dc.subject | Cognitive behavioural | |
dc.subject | Group | |
dc.title | One year follow-up of a pragmatic multi-centre randomised controlled trial of a group-based fatigue management programme (FACETS) for people with MS | |
dc.type | Journal Article | |
pubs.elements-id | 177507 | |
pubs.organisational-data | /AUT | |
pubs.organisational-data | /AUT/Health & Environmental Science |