Mobilisation or Immobilisation-Based Treatments for First Carpometacarpal Joint Osteoarthritis: A Systematic Review and Meta-Analysis With Subgroup Analyses

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aut.relation.journalHand Therapyen_NZ
aut.researcherMagni, Nicolo
dc.contributor.authorMagni, Nen_NZ
dc.contributor.authorMcNair, Pen_NZ
dc.contributor.authorRice, Den_NZ
dc.date.accessioned2022-05-24T23:50:58Z
dc.date.available2022-05-24T23:50:58Z
dc.date.copyright2022-06-01en_NZ
dc.date.issued2022-06-01en_NZ
dc.description.abstractIntroduction: Both joint mobilisation and immobilisation are thought to be effective in the treatment of first carpo metacarpal joint (CMCJ) osteoarthritis (OA). The objective of this review was to establish whether either intervention reduced pain and improved pinch strength in people with first CMCJ OA in the short term and assess whether one intervention is superior to the other. Method: This was a systematic review and meta-analysis. Seven databases were searched until May 2021. Only RCTs were included. The Cochrane Risk of Bias Tool and the Grade of Recommendations Assessment, Development and Evaluation system were utilised to rate the evidence. Random-effects meta-analysis with subgroup analyses were used. Results: Eight studies were included with a total of 417 participants. Mobilisation treatments included manual therapy with or without exercise while immobilisation interventions utilised thumb splinting with several different designs. Very low quality and low-quality evidence showed that mobilisation led to statistically but not clinically significant improvements in pain (standardised mean difference (SMD) = 0.53; 95% confidence interval (CI) = 0.03 to 1; I2 = 60%; p = 0.06) and pinch strength (SMD = 0.35; 95% CI = 0.03 to 0.7; I2 = 12%; p = 0.3) compared to placebo. Very low-quality and low-quality evidence showed no effect on pain and pinch strength compared to a control or no intervention. Subgroup analyses revealed no difference between interventions. Discussion: Neither mobilisation nor immobilisation alone led to clinically important improvements in pain or pinch strength in the short term in people with symptomatic first CMCJ OA. Neither therapeutic strategy appeared to be superior.
dc.identifier.citationHand Therapy, 2022, Vol. 27(2) 37–48.
dc.identifier.doi10.1177/17589983221083994
dc.identifier.issn1369-9571en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/15154
dc.publisherSAGEen_NZ
dc.relation.urihttps://journals.sagepub.com/doi/10.1177/17589983221083994
dc.rights© The Author(s) 2022. Under SAGE's Green Open Access policy, the Accepted Version of the article may be posted in the author's institutional repository and reuse is restricted to non-commercial and no derivative uses.
dc.rights.accessrightsOpenAccessen_NZ
dc.subjectBasal joint arthritis; Pain; Splints; Exercise; Orthotics
dc.titleMobilisation or Immobilisation-Based Treatments for First Carpometacarpal Joint Osteoarthritis: A Systematic Review and Meta-Analysis With Subgroup Analysesen_NZ
dc.typeJournal Article
pubs.elements-id453701
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Faculty of Health & Environmental Science
pubs.organisational-data/AUT/Faculty of Health & Environmental Science/School of Clinical Sciences
pubs.organisational-data/AUT/Faculty of Health & Environmental Science/School of Clinical Sciences/Physiotherapy Department
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