Global, Regional, and National Burden of Migraine and Tension-type Headache, 1990–2016: a Systematic Analysis for the Global Burden of Disease Study 2016

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aut.relation.endpage976
aut.relation.issue11en_NZ
aut.relation.journalThe Lancet Neurologyen_NZ
aut.relation.startpage954
aut.relation.volume17en_NZ
dark.contributor.authorStovner, LJen_NZ
dark.contributor.authorNichols, Een_NZ
dark.contributor.authorSteiner, TJen_NZ
dark.contributor.authorAbd-Allah, Fen_NZ
dark.contributor.authorAbdelalim, Aen_NZ
dark.contributor.authorAl-Raddadi, RMen_NZ
dark.contributor.authorAnsha, MGen_NZ
dark.contributor.authorBarac, Aen_NZ
dark.contributor.authorBensenor, IMen_NZ
dark.contributor.authorDoan, LPen_NZ
dark.contributor.authorEdessa, Den_NZ
dark.contributor.authorEndres, Men_NZ
dark.contributor.authorForeman, KJen_NZ
dark.contributor.authorGankpe, FGen_NZ
dark.contributor.authorGopalkrishna, Gen_NZ
dark.contributor.authorGoulart, ACen_NZ
dark.contributor.authorGupta, Ren_NZ
dark.contributor.authorHankey, GJen_NZ
dark.contributor.authorHay, SIen_NZ
dark.contributor.authorHegazy, MIen_NZ
dark.contributor.authorHilawe, EHen_NZ
dark.contributor.authorKasaeian, Aen_NZ
dark.contributor.authorKassa, DHen_NZ
dark.contributor.authorKhalil, Ien_NZ
dark.contributor.authorKhang, YHen_NZ
dark.contributor.authorKhubchandan, Jen_NZ
dark.contributor.authorKim, YJen_NZ
dark.contributor.authorKokubo, Yen_NZ
dark.contributor.authorMohammed, MAen_NZ
dark.contributor.authorMoradi-Lakeh, Men_NZ
dark.contributor.authorNguyen, HLTen_NZ
dark.contributor.authorNirayo, YLen_NZ
dark.contributor.authorQorbani, Men_NZ
dark.contributor.authorRanta, Aen_NZ
dark.contributor.authorRoba, KTen_NZ
dark.contributor.authorSafiri, Sen_NZ
dark.contributor.authorSantos, ISen_NZ
dark.contributor.authorSatpathy, Men_NZ
dark.contributor.authorSawhney, Men_NZ
dark.contributor.authorShiferaw, MSen_NZ
dark.contributor.authorShiue, Ien_NZ
dark.contributor.authorSmith, Men_NZ
dark.contributor.authorSzoeke, CEIen_NZ
dark.contributor.authorTruong, NTen_NZ
dark.contributor.authorVenketasubramanian, Nen_NZ
dark.contributor.authorweldegwergs, KGen_NZ
dark.contributor.authorWesterman, Ren_NZ
dark.contributor.authorWijeratne, Ten_NZ
dark.contributor.authorTran, BXen_NZ
dark.contributor.authorYonemoto, Nen_NZ
dark.contributor.authorFeigin, VLen_NZ
dark.contributor.authorVos, Ten_NZ
dark.contributor.authorMurray, CJLen_NZ
dc.date.accessioned2018-11-12T03:42:13Z
dc.date.available2018-11-12T03:42:13Z
dc.date.copyright2018en_NZ
dc.date.issued2018en_NZ
dc.description.abstractBackground: Through the Global Burden of Diseases, Injuries, and Risk Factors (GBD) studies, headache has emerged as a major global public health concern. We aimed to use data from the GBD 2016 study to provide new estimates for prevalence and years of life lived with disability (YLDs) for migraine and tension-type headache and to present the methods and results in an accessible way for clinicians and researchers of headache disorders. Methods: Data were derived from population-based cross-sectional surveys on migraine and tension-type headache. Prevalence for each sex and 5-year age group interval (ie, age 5 years to ≥95 years) at different time points from 1990 and 2016 in all countries and GBD regions were estimated using a Bayesian meta-regression model. Disease burden measured in YLDs was calculated from prevalence and average time spent with headache multiplied by disability weights (a measure of the relative severity of the disabling consequence of a disease). The burden stemming from medication overuse headache, which was included in earlier iterations of GBD as a separate cause, was subsumed as a sequela of either migraine or tension-type headache. Because no deaths were assigned to headaches as the underlying cause, YLDs equate to disability-adjusted life-years (DALYs). We also analysed results on the basis of the Socio-demographic Index (SDI), a compound measure of income per capita, education, and fertility. Findings: Almost three billion individuals were estimated to have a migraine or tension-type headache in 2016: 1·89 billion (95% uncertainty interval [UI] 1·71–2·10) with tension-type headache and 1·04 billion (95% UI 1·00–1·09) with migraine. However, because migraine had a much higher disability weight than tension-type headache, migraine caused 45·1 million (95% UI 29·0–62·8) and tension-type headache only 7·2 million (95% UI 4·6–10·5) YLDs globally in 2016. The headaches were most burdensome in women between ages 15 and 49 years, with migraine causing 20·3 million (95% UI 12·9–28·5) and tension-type headache 2·9 million (95% UI 1·8–4·2) YLDs in 2016, which was 11·2% of all YLDs in this age group and sex. Age-standardised DALYs for each headache type showed a small increase as SDI increased. Interpretation: Although current estimates are based on limited data, our study shows that headache disorders, and migraine in particular, are important causes of disability worldwide, and deserve greater attention in health policy debates and research resource allocation. Future iterations of this study, based on sources from additional countries and with less methodological heterogeneity, should help to provide stronger evidence of the need for action. Funding: Bill & Melinda Gates Foundation.en_NZ
dc.identifier.citationThe Lancet Neurology, 17(11), 954-976.
dc.identifier.doi10.1016/S1474-4422(18)30322-3en_NZ
dc.identifier.issn1474-4422en_NZ
dc.identifier.issn1474-4465en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/11982
dc.publisherElsevier
dc.relation.urihttps://www.sciencedirect.com/science/article/pii/S1474442218303223?via%3Dihub
dc.rights© 2018 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.
dc.rights.accessrightsOpenAccessen_NZ
dc.titleGlobal, Regional, and National Burden of Migraine and Tension-type Headache, 1990–2016: a Systematic Analysis for the Global Burden of Disease Study 2016en_NZ
dc.typeJournal Article
pubs.elements-id348676
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Health & Environmental Science
pubs.organisational-data/AUT/Health & Environmental Science/Public Health & Psych Studies
pubs.organisational-data/AUT/PBRF
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences/HY Public Health & Psychosocial Studies 2018 PBRF
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