Post-Concussion Symptoms in Complicated vs. Uncomplicated Mild Traumatic Brain Injury Patients at Three and Six Months Post-Injury: Results from the CENTER-TBI Study

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aut.relation.endpage1921
aut.relation.issue11en_NZ
aut.relation.journalJournal of Clinical Medicineen_NZ
aut.relation.startpage1921
aut.relation.volume8en_NZ
aut.researcherJones, Kelly
dc.contributor.authorVoormolen, DCen_NZ
dc.contributor.authorHaagsma, JAen_NZ
dc.contributor.authorPolinder, Sen_NZ
dc.contributor.authorMaas, AIRen_NZ
dc.contributor.authorSteyerberg, EWen_NZ
dc.contributor.authorVuleković, Pen_NZ
dc.contributor.authorSewalt, CAen_NZ
dc.contributor.authorGravesteijn, BYen_NZ
dc.contributor.authorCovic, Aen_NZ
dc.contributor.authorAndelic, Nen_NZ
dc.contributor.authorPlass, AMen_NZ
dc.contributor.authorvon Steinbuechel, Nen_NZ
dc.contributor.authorFeigin, VLen_NZ
dc.contributor.authorJones, KMen_NZ
dc.contributor.authorTheadom, Aen_NZ
dc.date.accessioned2022-10-12T01:47:58Z
dc.date.available2022-10-12T01:47:58Z
dc.date.copyright2019en_NZ
dc.date.issued2019en_NZ
dc.description.abstractThe aim of this study was to assess the occurrence of post-concussion symptoms and post-concussion syndrome (PCS) in a large cohort of patients after complicated and uncomplicated mild traumatic brain injury (mTBI) at three and six months post-injury. Patients were included through the prospective cohort study: Collaborative European NeuroTrauma Effectiveness Research (CENTER-TBI). Patients enrolled with mTBI (Glasgow Coma Scale 13–15) were further differentiated into complicated and uncomplicated mTBI based on the presence or absence of computed tomography abnormalities, respectively. The Rivermead Post-Concussion Symptoms Questionnaire (RPQ) assessed post-concussion symptoms and PCS according to the mapped ICD-10 classification method. The occurrence of post-concussion symptoms and syndrome at both time points was calculated. Chi square tests were used to test for differences between and within groups. Logistic regression was performed to analyse the association between complicated versus uncomplicated mTBI and the prevalence of PCS. Patients after complicated mTBI reported slightly more post-concussion symptoms compared to those after uncomplicated mTBI. A higher percentage of patients after complicated mTBI were classified as having PCS at three (complicated: 46% vs. uncomplicated: 35%) and six months (complicated: 43% vs. uncomplicated 34%). After adjusting for baseline covariates, the effect of complicated versus uncomplicated mTBI at three months appeared minimal: odds ratio 1.25 (95% confidence interval: 0.95–1.66). Although patients after complicated mTBI report slightly more post-concussion symptoms and show higher PCS rates compared to those after uncomplicated mTBI at three and six months, complicated mTBI was only found a weak indicator for these problems.en_NZ
dc.identifier.citationJournal of Clinical Medicine, 8(11), 1921. https://doi.org/10.3390/jcm8111921
dc.identifier.doi10.3390/jcm8111921en_NZ
dc.identifier.issn2077-0383en_NZ
dc.identifier.issn2077-0383en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/15515
dc.languageenen_NZ
dc.publisherMDPI AGen_NZ
dc.relation.urihttps://www.mdpi.com/2077-0383/8/11/1921en_NZ
dc.rightsThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
dc.rights.accessrightsOpenAccessen_NZ
dc.subjectComplicated mild traumatic brain injury; Post-concussion symptoms; Post-concussion syndrome; Traumatic brain injury
dc.titlePost-Concussion Symptoms in Complicated vs. Uncomplicated Mild Traumatic Brain Injury Patients at Three and Six Months Post-Injury: Results from the CENTER-TBI Studyen_NZ
dc.typeJournal Article
pubs.elements-id479918
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Faculty of Health & Environmental Sciences
pubs.organisational-data/AUT/Faculty of Health & Environmental Sciences/School of Clinical Sciences
pubs.organisational-data/AUT/PBRF
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences/HY Public Health & Psychosocial Studies 2018 PBRF
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