Investigating the Effects of Chiropractic Care on Resting-State EEG of MCI Patients
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Frontiers Media SA
Abstract
Introduction: Mild cognitive impairment (MCI) is a stage between health and dementia, with various symptoms including memory, language, and visuospatial impairment. Chiropractic, a manual therapy that seeks to improve the function of the body and spine, has been shown to affect sensorimotor processing, multimodal sensory processing, and mental processing tasks. Methods: In this paper, the effect of chiropractic intervention on Electroencephalogram (EEG) signals in patients with mild cognitive impairment was investigated. EEG signals from two groups of patients with mild cognitive impairment (n = 13 people in each group) were recorded pre- and post-control and chiropractic intervention. A comparison of relative power was done with the support vector machine (SVM) method and non-parametric cluster-based permutation test showing the two groups could be separately identified with high accuracy. Results: The highest accuracy was obtained in beta2 (25–35 Hz) and theta (4–8 Hz) bands. A comparison of different brain areas with the SVM method showed that the intervention had a greater effect on frontal areas. Also, interhemispheric coherence in all regions increased significantly after the intervention. The results of the Wilcoxon test showed that intrahemispheric coherence changes in frontal-occipital, frontal-temporal and right temporal-occipital regions were significantly different in two groups. Discussion: Comparison of the results obtained from chiropractic intervention and previous studies shows that chiropractic intervention can have a positive effect on MCI disease and using this method may slow down the progression of mild cognitive impairment to Alzheimer’s disease.Description
Keywords
Alzheimer’s disease, chiropractic, cluster-based permutation test, electroencephalography (EEG), mild cognitive impairment (MCI), 32 Biomedical and Clinical Sciences, 3209 Neurosciences, Brain Disorders, Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Aging, Behavioral and Social Science, Dementia, Alzheimer's Disease, Acquired Cognitive Impairment, Clinical Research, Neurodegenerative, Mental Health, Neurological, Mental health, 0601 Biochemistry and Cell Biology, 1109 Neurosciences, 1702 Cognitive Sciences, 3209 Neurosciences, 5202 Biological psychology
Source
Frontiers in Aging Neuroscience, ISSN: 1663-4365 (Print); 1663-4365 (Online), Frontiers Media SA, 16, 1406664-. doi: 10.3389/fnagi.2024.1406664
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© 2024 Ziloochi, Niazi, Amjad, Cade, Duehr, Ghani, Holt, Haavik and Shalchyan. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.