Neuropathic Pain in Hand Osteoarthritis: A Cross-Sectional Study

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aut.relation.endpage4439
aut.relation.issue19en_NZ
aut.relation.journalJournal of Clinical Medicineen_NZ
aut.relation.startpage4439
aut.relation.volume10en_NZ
aut.researcherMagni, Nicolo
dc.contributor.authorMagni, Nen_NZ
dc.contributor.authorCollier, Jen_NZ
dc.contributor.authorMcNair, Pen_NZ
dc.contributor.authorRice, DAen_NZ
dc.date.accessioned2021-09-29T03:30:14Z
dc.date.available2021-09-29T03:30:14Z
dc.description.abstractSymptomatic hand osteoarthritis (OA) is a severely debilitating condition. Neuropathic pain (NP) has been shown to be a factor affecting pain severity, hand function, psychological wellbeing, body schema, and the number of pain medications in people with OA of other joints. The aim of this study was to assess the prevalence of NP in symptomatic hand OA and assess its association with pain, hand function, measures of psychological wellbeing, sleep, body schema disturbances, and number of pain medications. Participants with symptomatic hand OA diagnosed through the American College of Rheumatology criteria, were recruited and completed a series of online questionnaires. These included the Douleur Neuropathique 4 interview (DN4-interview), Short Form Brief Pain Inventory (SF-BPI), Neglect-like Symptoms questionnaire, Functional Index of Hand Osteoarthritis (FIHOA), Centre for Epidemiologic Studies Depression Scale (CES-D), Pain Catastrophising Scale (PCS), and the Pittsburgh Sleep Quality Index (PSQI). Logistic regression with age, body mass index, and sex as covariates were utilised to assess differences between participants with and without NP as identified through the DN4-interview. Correlation analysis assessed the relationship between pain intensity, body schema alterations, and number of pain medications. A total of 121 participants were included in the present study. Forty-two percent of participants presented with NP. Participants with NP reported higher levels of worst pain (OR: 10.2 95% CI: 2.2 to 48.5; p = 0.007). Worst pain intensity correlated with the number of pain medications (rho = 0.2; p = 0.04), and neglect-like symptoms (rho = 0.4; p < 0.0001). No difference between phenotypes was shown for catastrophising, function, depression, neglect-like symptoms, pain interference, or sleep. A large proportion of people with symptomatic hand OA present with NP. This phenotype is characterised by greater levels of pain intensity. Pain intensity is associated with number of pain relief medications and body schema alteration. Psychological factors, hand function, and sleep do not appear to be affected by the presence of NP.en_NZ
dc.identifier.citationJournal of Clinical Medicine, 10(19), 4439. doi:10.3390/jcm10194439
dc.identifier.doi10.3390/jcm10194439en_NZ
dc.identifier.issn2077-0383en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/14540
dc.languageenen_NZ
dc.publisherMDPI AGen_NZ
dc.relation.urihttps://www.mdpi.com/2077-0383/10/19/4439
dc.rights© 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/).
dc.rights.accessrightsOpenAccessen_NZ
dc.subjectChronic pain; Musculoskeletal pain; Osteoarthritis
dc.titleNeuropathic Pain in Hand Osteoarthritis: A Cross-Sectional Studyen_NZ
dc.typeJournal Article
pubs.elements-id440875
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Faculty of Health & Environmental Science
pubs.organisational-data/AUT/Faculty of Health & Environmental Science/School of Clinical Sciences
pubs.organisational-data/AUT/Faculty of Health & Environmental Science/School of Clinical Sciences/Physiotherapy Department
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