Using Recursive Logistic Regression to Develop a Patient-reported Outcome in Non-cystic Fibrosis Bronchiectasis
aut.researcher | Wheldon, Mark | |
dc.contributor.author | Wheldon, MC | en_NZ |
dc.contributor.author | Vandal, AC | en_NZ |
dc.contributor.author | Bourien, A | en_NZ |
dc.contributor.author | Jayaram, L | en_NZ |
dc.contributor.author | Karalus, N | en_NZ |
dc.contributor.author | Tong, C | en_NZ |
dc.contributor.author | Hockey, H | en_NZ |
dc.contributor.author | Wong, C | en_NZ |
dc.date.accessioned | 2017-08-06T23:03:40Z | |
dc.date.available | 2017-08-06T23:03:40Z | |
dc.date.copyright | 2015-11-24 | en_NZ |
dc.date.issued | 2015-11-24 | en_NZ |
dc.description.abstract | Many patient reported outcomes for non-cystic fibrosis bronchiectasis are time-consuming self-report surveys such as the St. George's Respiratory Questionnaire. Using data from the EMBRACE multi-center RCT, we use recursive logistic regression to develop a new outcome that only requires responses to three simple questions about pulmonary symptoms (sputum volume, sputum purulence, and dyspnoea). The low response burden means that the outcome can be calculated for each day of follow-up in real-time. The new outcome is constructed such that it is a good predictor of event-based exacerbation, a sustained worsening of condition requiring treatment with antibiotics, and validated against self-reported quality of life. | en_NZ |
dc.identifier.citation | 2015 Joint NZSA+ORSNZ Conference, 24-26 November, University of Canterbury, New Zealand | en_NZ |
dc.identifier.uri | https://hdl.handle.net/10292/10725 | |
dc.publisher | The New Zealand Statistical Association (NZSA) | |
dc.relation.uri | https://secure.orsnz.org.nz/conf49/index.php | |
dc.rights | NOTICE: this is the author’s version of a work that was accepted for publication. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in (see Citation). The original publication is available at (see Publisher's Version). | |
dc.rights.accessrights | OpenAccess | en_NZ |
dc.title | Using Recursive Logistic Regression to Develop a Patient-reported Outcome in Non-cystic Fibrosis Bronchiectasis | en_NZ |
dc.type | Conference Contribution | |
pubs.elements-id | 193617 | |
pubs.organisational-data | /AUT | |
pubs.organisational-data | /AUT/Health & Environmental Science |
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