Using Recursive Logistic Regression to Develop a Patient-reported Outcome in Non-cystic Fibrosis Bronchiectasis

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aut.researcherWheldon, Mark
dc.contributor.authorWheldon, MCen_NZ
dc.contributor.authorVandal, ACen_NZ
dc.contributor.authorBourien, Aen_NZ
dc.contributor.authorJayaram, Len_NZ
dc.contributor.authorKaralus, Nen_NZ
dc.contributor.authorTong, Cen_NZ
dc.contributor.authorHockey, Hen_NZ
dc.contributor.authorWong, Cen_NZ
dc.date.accessioned2017-08-06T23:03:40Z
dc.date.available2017-08-06T23:03:40Z
dc.date.copyright2015-11-24en_NZ
dc.date.issued2015-11-24en_NZ
dc.description.abstractMany patient reported outcomes for non-cystic fibrosis bronchiectasis are time-consuming self-report surveys such as the St. George's Respiratory Questionnaire. Using data from the EMBRACE multi-center RCT, we use recursive logistic regression to develop a new outcome that only requires responses to three simple questions about pulmonary symptoms (sputum volume, sputum purulence, and dyspnoea). The low response burden means that the outcome can be calculated for each day of follow-up in real-time. The new outcome is constructed such that it is a good predictor of event-based exacerbation, a sustained worsening of condition requiring treatment with antibiotics, and validated against self-reported quality of life.en_NZ
dc.identifier.citation2015 Joint NZSA+ORSNZ Conference, 24-26 November, University of Canterbury, New Zealanden_NZ
dc.identifier.urihttps://hdl.handle.net/10292/10725
dc.publisherThe New Zealand Statistical Association (NZSA)
dc.relation.urihttps://secure.orsnz.org.nz/conf49/index.php
dc.rightsNOTICE: this is the author’s version of a work that was accepted for publication. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in (see Citation). The original publication is available at (see Publisher's Version).
dc.rights.accessrightsOpenAccessen_NZ
dc.titleUsing Recursive Logistic Regression to Develop a Patient-reported Outcome in Non-cystic Fibrosis Bronchiectasisen_NZ
dc.typeConference Contribution
pubs.elements-id193617
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Health & Environmental Science
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