Biocompatible Polymer for Self-Humidification

Al-Jumaily, Ahmed M
Bartual, Sandra
Weerasinghe, NT
Item type
Journal Article
Degree name
Journal Title
Journal ISSN
Volume Title

Lung supportive devices (LSDs) have been extensively utilized in treating patients diagnosed with various respiratory disorders. However, these devices can cause moisture depletion in the upper airway by interfering with the natural lubrication and air conditioning process. To remedy this, current technologies implement heated humidification processes, which are bulky, costly, and nonfriendly. However, it has been demonstrated that in a breath cycle, the amount of water vapor in the exhaled air is of a similar quantity to the amount needed to humidify the inhaled air. This research proposes to trap the moisture from exhaled air and reuse it during inhalation by developing a state-of-the-art hydrophilic/hydrophobic polymer tuned to deliver this purpose. Using the atom transfer radical polymerization (ATRP) method, a substrate was successfully created by incorporating poly (N-isopropyl acrylamide) (PNIPAM) onto cotton. The fabricated material exhibited a water vapor release rate of 24.2 ± 1.054%/min at 32 °C, indicating its ability to humidify the inhaled air effectively. These findings highlight the potential of the developed material as a promising solution for applications requiring rapid moisture recovery.

CPAP , humidification , hydrophilic , hydrophobic , LCST , CPAP , LCST , humidification , hydrophilic , hydrophobic , 40 Engineering , 4016 Materials Engineering , Lung , Biotechnology , Respiratory , 03 Chemical Sciences , 09 Engineering , 34 Chemical sciences , 40 Engineering
Polymers (Basel), ISSN: 2073-4360 (Print); 2073-4360 (Online), MDPI AG, 15(20), 4101-4101. doi: 10.3390/polym15204101
Rights statement
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (