Foot Pain, Impairment and Disability in Patients With Acute Gout Flares; A Prospective Observational Study

aut.researcherRome, Keith
dc.contributor.authorRome, K
dc.contributor.authorFrecklington, M
dc.contributor.authorRome, K
dc.contributor.authorMcNair, PJ
dc.contributor.authorGow, P
dc.contributor.authorDalbeth, N
dc.date.accessioned2011-10-20T19:16:23Z
dc.date.available2012-09-03T21:00:58Z
dc.date.copyright2011
dc.date.issued2011
dc.description.abstractObjectives: The aim of this study was to evaluate the impact of acute gout on foot pain, impairment and disability. Methods: This prospective observational study recruited 20 patients with acute gout flares. Patients were recruited from emergency departments, hospital wards and rheumatology outpatient clinics throughout Auckland, New Zealand. Patients were recruited at the time of the flare (baseline visit) and then reassessed at a follow-up visit once the acute flare had resolved 6-8 weeks after the initial assessment. Joint counts, C-reactive protein and serum urate were recorded at both visits. General and foot-specific outcome measures were also recorded at each visit including pain visual analogue scale, Health Assessment Questionnaire (HAQ)-II, Lower Limb Tasks Questionnaire, and the Leeds Foot Impact Scale. Results: The foot was affected by acute gout in 14 (70%) patients. Objective measures of joint inflammation including swollen and tender joint counts and C-reactive protein significantly improved at the follow-up visit, compared with the baseline visit. At baseline, high levels of foot pain, impairment and disability were reported. All patient-reported outcome measures of general and foot-specific musculoskeletal function improved at the follow-up visit compared with the baseline visit. However, pain, impairment and disability scores did not entirely normalise after resolution of the acute gout flare. Conclusions: Patients with acute gout flares experience severe foot pain, impairment and disability. These data provide further support for improved management of gout to prevent the consequences of poorly controlled disease.
dc.identifier.citationArthritis Care & Research (March 2012). Volume 64 (Issue 3), pages 384–388.
dc.identifier.doi10.1002/acr.20670
dc.identifier.issn2151-464X (print) 2151-4658 (online)
dc.identifier.urihttps://hdl.handle.net/10292/2412
dc.publisherJohn Wiley & Sons
dc.relation.urihttp://dx.doi.org/10.1002/acr.20670
dc.rightsCopyright © 2011 John Wiley & Sons. All rights reserved. Authors retain the right to place his/her pre-publication version of the work on a personal website or institutional repository. This article may not exactly replicate the final version published in (please see citation) as it is not a copy of this record. An electronic version of this article can be found online at: (Please see Publisher’s Version)
dc.rights.accessrightsOpenAccess
dc.subjectGout
dc.subjectPain
dc.subjectFoot
dc.subjectDisability
dc.subjectJoint
dc.subjectOutcome measures
dc.titleFoot Pain, Impairment and Disability in Patients With Acute Gout Flares; A Prospective Observational Study
dc.typeJournal Article
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Health & Environmental Science
pubs.organisational-data/AUT/PBRF Researchers
pubs.organisational-data/AUT/PBRF Researchers/Health & Environmental Sciences PBRF Researchers
pubs.organisational-data/AUT/PBRF Researchers/Health & Environmental Sciences PBRF Researchers/HES R & O Podiatry
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