The Overlapping Burden of the Three Leading Causes of Disability and Death in Sub-Saharan African Children

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aut.relation.articlenumber7457en_NZ
aut.relation.issue1en_NZ
aut.relation.journalNature Communicationsen_NZ
aut.relation.volume13en_NZ
aut.researcherFeigin, Valery
dc.contributor.authorReiner, RCen_NZ
dc.contributor.authorWelgan, CAen_NZ
dc.contributor.authorTroeger, CEen_NZ
dc.contributor.authorBaumann, MMen_NZ
dc.contributor.authorWeiss, DJen_NZ
dc.contributor.authorDeshpande, Aen_NZ
dc.contributor.authorBlacker, BFen_NZ
dc.contributor.authorMiller-Petrie, MKen_NZ
dc.contributor.authorEarl, Len_NZ
dc.contributor.authorBhatt, Sen_NZ
dc.contributor.authorAbolhassani, Hen_NZ
dc.contributor.authorAbosetugn, AEen_NZ
dc.contributor.authorAbu-Gharbieh, Een_NZ
dc.contributor.authorAdekanmbi, Ven_NZ
dc.contributor.authorAdetokunboh, OOen_NZ
dc.contributor.authorAghaali, Men_NZ
dc.contributor.authorAji, Ben_NZ
dc.contributor.authorAlahdab, Fen_NZ
dc.contributor.authorAl-Aly, Zen_NZ
dc.contributor.authorAlhassan, RKen_NZ
dc.contributor.authorAli, Sen_NZ
dc.contributor.authorAlizade, Hen_NZ
dc.contributor.authorAljunid, SMen_NZ
dc.contributor.authorAlmasi-Hashiani, Aen_NZ
dc.contributor.authorAl-Mekhlafi, HMen_NZ
dc.contributor.authorAltirkawi, KAen_NZ
dc.contributor.authorAlvis-Guzman, Nen_NZ
dc.contributor.authorAmare, ATen_NZ
dc.contributor.authorAmini, Sen_NZ
dc.contributor.authorAmugsi, DAen_NZ
dc.contributor.authorAncuceanu, Ren_NZ
dc.contributor.authorAndrei, CLen_NZ
dc.contributor.authorAnsari, Fen_NZ
dc.contributor.authorAnvari, Den_NZ
dc.contributor.authorAppiah, SCYen_NZ
dc.contributor.authorArabloo, Jen_NZ
dc.contributor.authorAremu, Oen_NZ
dc.contributor.authorAtout, MMWen_NZ
dc.contributor.authorAusloos, Men_NZ
dc.contributor.authorAusloos, Fen_NZ
dc.contributor.authorAyanore, MAen_NZ
dc.contributor.authorAynalem, YAen_NZ
dc.contributor.authorAzene, ZNen_NZ
dc.contributor.authorBadawi, Aen_NZ
dc.contributor.authorBaig, AAen_NZ
dc.contributor.authorBanach, Men_NZ
dc.contributor.authorBedi, Nen_NZ
dc.contributor.authorBhagavathula, ASen_NZ
dc.contributor.authorBhandari, Den_NZ
dc.contributor.authorBhardwaj, Nen_NZ
dc.contributor.authorBhardwaj, Pen_NZ
dc.contributor.authorBhattacharyya, Ken_NZ
dc.contributor.authorBhutta, ZAen_NZ
dc.contributor.authorBijani, Aen_NZ
dc.contributor.authorBirhanu, TTMen_NZ
dc.contributor.authorBitew, ZWen_NZ
dc.contributor.authorBoloor, Aen_NZ
dc.contributor.authorBrady, OJen_NZ
dc.contributor.authorButt, ZAen_NZ
dc.contributor.authorCar, Jen_NZ
dc.contributor.authorCarvalho, Fen_NZ
dc.contributor.authorCasey, DCen_NZ
dc.contributor.authorChattu, VKen_NZ
dc.contributor.authorChowdhury, MAKen_NZ
dc.contributor.authorChu, DTen_NZ
dc.contributor.authorCoelho, CHen_NZ
dc.contributor.authorCook, AJen_NZ
dc.contributor.authorDamiani, Gen_NZ
dc.contributor.authorDaoud, Fen_NZ
dc.contributor.authorGela, JDen_NZ
dc.contributor.authorDarwish, AHen_NZ
dc.contributor.authorDaryani, Aen_NZ
dc.contributor.authorDas, JKen_NZ
dc.contributor.authorDavis Weaver, Nen_NZ
dc.contributor.authorDeribe, Ken_NZ
dc.contributor.authorDesalew, Aen_NZ
dc.contributor.authorDharmaratne, SDen_NZ
dc.contributor.authorDianatinasab, Men_NZ
dc.contributor.authorDiaz, Den_NZ
dc.contributor.authorDjalalinia, Sen_NZ
dc.contributor.authorDorostkar, Fen_NZ
dc.contributor.authorDubljanin, Een_NZ
dc.contributor.authorDuko, Ben_NZ
dc.contributor.authorDwyer-Lindgren, Len_NZ
dc.contributor.authorEffiong, Aen_NZ
dc.contributor.authorEl Sayed Zaki, Men_NZ
dc.contributor.authorEl Tantawi, Men_NZ
dc.contributor.authorEnany, Sen_NZ
dc.contributor.authorFattahi, Nen_NZ
dc.contributor.authorFeigin, VLen_NZ
dc.contributor.authorFernandes, Een_NZ
dc.contributor.authorFerrara, Pen_NZ
dc.contributor.authorFischer, Fen_NZ
dc.contributor.authorFoigt, NAen_NZ
dc.contributor.authorFolayan, MOen_NZ
dc.contributor.authorForoutan, Men_NZ
dc.contributor.authorFrostad, JJen_NZ
dc.contributor.authorFukumoto, Ten_NZ
dc.contributor.authorGaidhane, AMen_NZ
dc.contributor.authorGebrekrstos, HGGKen_NZ
dc.date.accessioned2023-01-10T01:32:58Z
dc.date.available2023-01-10T01:32:58Z
dc.date.copyright2022en_NZ
dc.date.issued2022en_NZ
dc.description.abstractDespite substantial declines since 2000, lower respiratory infections (LRIs), diarrhoeal diseases, and malaria remain among the leading causes of nonfatal and fatal disease burden for children under 5 years of age (under 5), primarily in sub-Saharan Africa (SSA). The spatial burden of each of these diseases has been estimated subnationally across SSA, yet no prior analyses have examined the pattern of their combined burden. Here we synthesise subnational estimates of the burden of LRIs, diarrhoea, and malaria in children under-5 from 2000 to 2017 for 43 sub-Saharan countries. Some units faced a relatively equal burden from each of the three diseases, while others had one or two dominant sources of unit-level burden, with no consistent pattern geographically across the entire subcontinent. Using a subnational counterfactual analysis, we show that nearly 300 million DALYs could have been averted since 2000 by raising all units to their national average. Our findings are directly relevant for decision-makers in determining which and targeting where the most appropriate interventions are for increasing child survival.en_NZ
dc.identifier.citationNature Communications 13, 7457 (2022). https://doi.org/10.1038/s41467-022-34240-6
dc.identifier.doi10.1038/s41467-022-34240-6en_NZ
dc.identifier.issn2041-1723en_NZ
dc.identifier.issn2041-1723en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/15786
dc.publisherSpringer Nature
dc.relation.urihttps://www.nature.com/articles/s41467-022-34240-6
dc.rights.accessrightsOpenAccessen_NZ
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.subjectBiogeography; Epidemiology; Infectious diseases; Malaria
dc.titleThe Overlapping Burden of the Three Leading Causes of Disability and Death in Sub-Saharan African Childrenen_NZ
dc.typeJournal Article
pubs.elements-id487660
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Faculty of Health & Environmental Sciences
pubs.organisational-data/AUT/Faculty of Health & Environmental Sciences/School of Clinical Sciences
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