COVID-19 Testing and Diagnosis in Children Under Six Years of Age: A Systematic Review

dc.contributor.advisorFoster, Mandie
dc.contributor.authorUre, Kirsty
dc.date.accessioned2024-06-24T04:12:34Z
dc.date.available2024-06-24T04:12:34Z
dc.date.issued2024
dc.description.abstractIntroduction: Severe acute respiratory syndrome was first detected in 2003 and escalated in 2019 with COVID-19 causing a worldwide pandemic. This new virus presented challenges in diagnosis, especially in those under 6 years of age. While often classified as a mild disease in children, COVID-19 still presents significant health risks in the young, especially for children under 1 year of age and those with pre-existing comorbidities. Because of this, clinical guidelines and protocols addressing COVID-19 testing in preschool- aged children became necessary to direct evidence-based practice. Aim: The aim of this systematic review was to explore COVID-19 testing and diagnosis in children under 6 years of age from international peer-reviewed published manuscripts to facilitate a wider and more thorough understanding of this practice from a diverse sample of parents, children, and health care providers to inform and direct practice within Aotearoa/New Zealand. Methods: A systematic review was undertaken based on guidelines by Siddaway et al. (2019). Extant empirical research published in peer-reviewed journals from 2020–2024 on COVID-19 testing in children under 6 years of age was identified from Scopus, CINAHL, MEDLINE via PubMed, and PsycInfo via Ovid databases. Data were analysed using deductive thematic analysis. Findings: Fourteen studies involving over 5,000 participants were included. Deductive content analysis identified seven key areas: 1. Symptomology, 2. Diagnostic tests, 4. Efficacy and acceptability of testing, 4. Viral loads, 5. Vulnerability/Risk factors, 6. Health outcomes, and 7. Recommendations. Conclusion: While common symptoms such as fever and cough are prevalent in children under 6 years of age infected with COVID-19, symptomology alone is not a foolproof diagnostic tool. Additional diagnostic testing, such as nasopharyngeal swabs and polymerase chain reaction testing, is complementary to diagnosis. However, an understanding of the risk factors for contracting COVID-19, as well as the vulnerability and health outcomes of children with COVID-19, is important to consider. Implications for practice: Common symptomology for children under 6 years of age includes fever and cough; however, these symptoms are also common for other viruses. A history of exposure to COVID-19 is the most frequent positive predictive factor for infection. An assessment of the child before any decisions on diagnostic testing is useful.
dc.identifier.urihttp://hdl.handle.net/10292/17696
dc.language.isoen
dc.publisherAuckland University of Technology
dc.rights.accessrightsOpenAccess
dc.titleCOVID-19 Testing and Diagnosis in Children Under Six Years of Age: A Systematic Review
dc.typeThesis
thesis.degree.grantorAuckland University of Technology
thesis.degree.nameMaster of Health Practice
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