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Impaired Olfactory Function: Loss of Smell and Insight Into Neurodegenerative Disorders

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Dissertation(359.73 KB)

Date

2022

Authors

Supervisor

Pederson, Mangor

Item type

Dissertation

Degree name

Bachelor of Health Science (Honours)

Journal Title

Journal ISSN

Volume Title

Publisher

Auckland University of Technology

Abstract

This study aims to investigate the possible association between olfactory function (‘sense of smell’) impairment in neurodegenerative disorders such as Alzheimer's disease and Parkinson’s disease, through a systematic review of relevant medical academia. Findings were overall consistent among research articles, and suggest that early stages neurodegenerative diseases could be identified through a poor sense of smell, which was simultaneously linked to lower volumes of the olfactory bulb. Implications suggest that inexpensive and noninvasive olfactory function assessments would be excellent biomarkers to aid in clinical diagnosis.

Description

Keywords

Human olfactory system; Olfaction; Olfactory receptor neurons; Olfactory assessment; Smell; Tau; Neurofibrillary tangles; Odour identification; Temporal information; Alzheimer's disease; Parkinson’s disease; neurodegenerative disorders

Source

DOI

Publisher's version

Rights statement

Permanent link

https://hdl.handle.net/10292/15085

Collections

Bachelor with Honours Dissertations - open access