An Investigation into the Human Upper Airways Humidification

aut.embargoYesen_NZ
aut.filerelease.date2025-07-05
aut.thirdpc.containsNoen_NZ
dc.contributor.advisorAl-Jumaily, Ahmed
dc.contributor.advisorRamos, Maximiano
dc.contributor.advisorChen, Jack
dc.contributor.authorGrau Bartual, Sandra
dc.date.accessioned2019-07-05T01:55:34Z
dc.date.available2019-07-05T01:55:34Z
dc.date.copyright2019
dc.date.issued2019
dc.date.updated2019-07-05T00:05:36Z
dc.description.abstractThis research focuses on the analysis of the human upper airway humidification looking on one hand at the natural humidification or air conditioning process and on the other hand at the external humidification. Lung supportive devices are widely used to restore the breathing cycle and provide proper ventilation to patients. These devices introduce compressed room air into the respiratory system and generate a positive pressure inside the respiratory system and a turbulent effect to keep the airways open which distorts the natural lubrication and humidification. Hence, lung supportive devices incorporate a convective heated humidifier which provides external humidification to the patients to alleviate the upper airway dryness produced by the compressed airflow. However, the humidifier makes the devices bulky and patients are still reporting side effects after the therapy. Therefore, the purpose of this research is to investigate the effect of the positive airway pressure on the human upper airway epithelium, extrapolate the results to the entire human upper airways and develop a miniaturized, eco-friendly and affordable selfhumidifying device able to overcome the dryness side effect and replace the actual convective heated humidifier.en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/12634
dc.language.isoenen_NZ
dc.publisherAuckland University of Technology
dc.rights.accessrightsOpenAccess
dc.subjectAir conditioningen_NZ
dc.subjectCPAPen_NZ
dc.subjectCalu-3 cellsen_NZ
dc.subjectRPMI 2650en_NZ
dc.subjectPressure oscillationsen_NZ
dc.subjectPNIPAMen_NZ
dc.subjectSelf-humidificationen_NZ
dc.titleAn Investigation into the Human Upper Airways Humidificationen_NZ
dc.typeThesisen_NZ
thesis.degree.grantorAuckland University of Technology
thesis.degree.levelDoctoral Theses
thesis.degree.nameDoctor of Philosophyen_NZ
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