Marquez-Romero, Juan ManuelRomo-Martínez, JessicaHernández-Curiel, BernardoRuiz-Franco, AngélicaKrishnamurthi, RitaFeigin, Valery2024-03-182024-03-182024-03-11Arq Neuropsiquiatr, ISSN: 0004-282X (Print); 1678-4227 (Online), Georg Thieme Verlag KG, 82(3), 1-5. doi: 10.1055/s-0044-17796910004-282X1678-4227http://hdl.handle.net/10292/17334BACKGROUND:  Genetic factors influence the risk of developing stroke. Still, it is unclear whether this risk is intrinsically high in certain people or if nongenetic factors explain it entirely. OBJECTIVE:  To compare the risk of stroke in kin and nonkin caregivers. METHODS:  In a cross-sectional study using the Stroke Riskometer app (AUT Ventures Limited, Auckland, AUK, New Zealand), we determined the 5- and 10-year stroke risk (SR) among caregivers of stroke inpatients. The degree of kinship was rated with a score ranging from 0 to 50 points. RESULTS:  We studied 278 caregivers (69.4% of them female) with a mean age of 47.5 ± 14.2 years. Kin caregivers represented 70.1% of the sample, and 49.6% of them were offspring. The median SR at 5 years was of 2.1 (range: 0.35-17.3) versus 1.73 (range: 0.04-29.9), and of 4.0 (range: 0.45-38.6) versus 2.94 (range: 0.05-59.35) at 10 years for the nonkin and kin caregivers respectively. In linear logistic regression controlled for the age of the caregivers, adding the kinship score did not increase the overall variability of the model for the risk at 5 years (R2 = 0.271; p = 0.858) nor the risk at 10 years (R2 = 0.376; p = 0.78). CONCLUSION:  Caregivers of stroke patients carry a high SR regardless of their degree of kinship.© 2024. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)https://creativecommons.org/licenses/by/4.0/32 Biomedical and Clinical Sciences3209 Neurosciences3202 Clinical SciencesBrain DisordersStrokeStroke1103 Clinical Sciences1702 Cognitive SciencesNeurology & Neurosurgery3202 Clinical sciences3209 NeurosciencesHumansFemaleAdultMiddle AgedChild, PreschoolCaregiversCross-Sectional StudiesStrokeHumansCross-Sectional StudiesAdultMiddle AgedChild, PreschoolCaregiversFemaleStrokeHumansFemaleAdultMiddle AgedChild, PreschoolCaregiversCross-Sectional StudiesStrokeJournal ArticleOpenAccess10.1055/s-0044-1779691