Lozano, RNaghavi, MForeman, KLim, SShibuya, KAboyans, VAbraham, JAdair, TAggarwal, RAhn, SYAlvarado, MAnderson, HRAnderson, LMAndrews, KGAtkinson, CBaddour, LMBarker-Collo, SBartels, DHBell, MLBenjamin, EJBennett, DBhalla, KBikbov, BBin Abdulhak, ABirbeck, GBlyth, FBolliger, IBoufous, SBucello, CBurch, MBurney, PCarapetis, JChen, HChou, DChugh, SSCoffeng, LEColan, SDColquhoun, SColson, KECondon, JConnor, MDCooper, LTCorriere, MCortinovis, Mde Vaccaro, KCCouser, WCowie, BCCriqui, MHCross, MDabhadkar, KCDahodwala, NDe Leo, DDegenhardt, LDelossantos, ADenenberg, JDes Jarlais, DCDharmaratne, SDDorsey, ERDriscoll, TDuber, HEbel, BErwin, PJEspindola, PEzzati, MFeigin, VFlaxman, ADForouzanfar, MHFowkes, FGFranklin, RFransen, MFreeman, MKGabriel, SEGakidou, EGaspari, FGillum, RFGonzalez-Medina, DHalasa, YAHaring, DHarrison, JEHavmoeller, RHay, RJHoen, BHotez, PJHoy, DJacobsen, KHJames, SLJasrasaria, RJayaraman, SJohns, NKarthikeyan, GKassebaum, NKeren, AKhoo, JPKnowlton, LMKobusingye, OKoranteng, AKrishnamurthi, RLipnick, MLipshultz, SEOhno, SLMabweijano, JMacIntyre, MFMallinger, LMarch, LMarks, GBMarks, RMatsumori, AMatzopoulos, RMayosi, BMMcAnulty, JHMcDermott, MMMcGrath, JMensah, GAMerriman, TRMichaud, CMiller, MMiller, TRMock, CMocumbi, AOMokdad, AAMoran, AMulholland, KNair, MNNaldi, LNarayan, KMNasseri, KNorman, PO'Donnell, MOmer, SBOrtblad, KOsborne, ROzgediz, DPahari, BPandian, JDRivero, APPadilla, RPPerez-Ruiz, FPerico, NPhillips, DPierce, KPope, CAPorrini, EPourmalek, FRaju, MRanganathan, DRehm, JTRein, DBRemuzzi, GRivara, FPRoberts, TDe León, FRRosenfeld, LCRushton, LSacco, RLSalomon, JASampson, USanman, ESchwebel, DCSegui-Gomez, MShepard, DSSingh, DSingleton, JSliwa, KSmith, ESteer, ATaylor, JAThomas, BTleyjeh, IMTowbin, JATruelsen, TUndurraga, EAVenketasubramanian, NVijayakumar, LVos, TWagner, GRWang, MWang, WWatt, KWeinstock, MAWeintraub, RWilkinson, JDWoolf, ADWulf, SYeh, PHYip, PZabetian, AZheng, ZJLopez, ADMurray, CJ2020-11-112020-11-1120132013The Lancet, 380(9859), 2095-2128.1474-547Xhttps://hdl.handle.net/10292/13775Background Reliable and timely information on the leading causes of death in populations, and how these are changing, is a crucial input into health policy debates. In the Global Burden of Diseases, Injuries, and Risk Factors Study 2010 (GBD 2010), we aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex.© This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ This is the accepted version of an article published in The Lancet. The publisher's version of the article can be found here: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(12)61728-0/fulltextJournal ArticleOpenAccess10.1016/S0140-6736(12)61728-0