Faulkner, Josh WTheadom, AliceSnell, Deborah LWilliams, Matt N2023-08-022023-08-022023-07-20Frontiers in Neurology, ISSN: 1664-2295 (Print); 1664-2295 (Online), Frontiers Media SA, 14, 1226367-. doi: 10.3389/fneur.2023.12263671664-22951664-2295http://hdl.handle.net/10292/16508Objective: A latent disease explanation cannot exclusively explain post-concussion symptoms after mild traumatic brain injury (mTBI). Network analysis offers an alternative form of explanation for relationships between symptoms. The study aimed to apply network analysis to post-concussion symptoms in two different mTBI cohorts; an acute treatment-seeking sample and a sample 10 years post-mTBI. Method: The treatment-seeking sample (n = 258) were on average 6 weeks post-injury; the 10 year post mTBI sample (n = 193) was derived from a population-based incidence and outcomes study (BIONIC). Network analysis was completed on post-concussion symptoms measured using the Rivermead Post-Concussion Questionnaire. Results: In the treatment-seeking sample, frustration, blurred vision, and concentration difficulties were central to the network. These symptoms remained central in the 10 year post mTBI sample. A Network Comparison Test revealed evidence of a difference in network structure across the two samples (p = 0.045). However, the only symptoms that showed significant differences in strength centrality across samples were irritability and restlessness. Conclusion: The current findings suggest that frustration, blurred vision and concentration difficulties may have an influential role in the experience and maintenance of post-concussion symptoms. The impact of these symptoms may remain stable over time. Targeting and prioritising the management of these symptoms may be beneficial for mTBI rehabilitation.http://creativecommons.org/licenses/by/4.0/5203 Clinical and Health Psychology52 PsychologyNeurosciencesTraumatic Head and Spine InjuryBrain DisordersClinical ResearchPhysical Injury - Accidents and Adverse EffectsTraumatic Brain Injury (TBI)Mental health1103 Clinical Sciences1109 Neurosciences1701 Psychology3202 Clinical sciences3209 Neurosciences5202 Biological psychologyJournal ArticleOpenAccess10.3389/fneur.2023.1226367