Browsing Open Research by Author "Cowan, BR"

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Treatment With a Copper-selective Chelator Causes Substantive Improvement in Cardiac Function of Diabetic Rats With Left-ventricular Impairment

Lu, J; Pontré, B; Pickup, S; Choong, SY; Li, M; Xu, H; Gamble, GD; Phillips, AR; Cowan, BR; Young, AA; Cooper, GJ (BioMed Central (BMC), 2013)

Background Defective copper regulation is implicated as a causative mechanism of organ damage in diabetes. Treatment with trientine, a divalent-copper-selective chelator, improves arterial and renal structure/function in ...