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dc.contributor.authorYu, Jen_NZ
dc.contributor.authorLi, Qen_NZ
dc.contributor.authorWu, Jen_NZ
dc.contributor.authorYang, Xen_NZ
dc.contributor.authorYang, Sen_NZ
dc.contributor.authorZhu, Wen_NZ
dc.contributor.authorLiu, Yen_NZ
dc.contributor.authorTang, Wen_NZ
dc.contributor.authorNie, Sen_NZ
dc.contributor.authorHassouna, Aen_NZ
dc.contributor.authorWhite, WLen_NZ
dc.contributor.authorZhao, Yen_NZ
dc.contributor.authorLu, Jen_NZ
dc.date.accessioned2021-07-06T03:22:22Z
dc.date.available2021-07-06T03:22:22Z
dc.date.copyright2021en_NZ
dc.identifier.citationFrontiers in Nutrition. 8:636930. doi: 10.3389/fnut.2021.636930
dc.identifier.issn2296-861Xen_NZ
dc.identifier.urihttp://hdl.handle.net/10292/14349
dc.description.abstractFucoidan is a multifunctional marine carbohydrate polymer that differs in its chemical composition and bioactivity both between seaweed species and within species from different locations across the globe. In this study, fucoidan was extracted from the sporophyll of Undaria pinnatifida grown in Weihai, Shandong Province, China. Fucoidan fractions with molecular weight cutoffs (MWCO) of >300 kDa and <10 kDa were obtained via dialysis. The fucoidan standard from Sigma (Fstd, ≥95, CAS: 9072-19-9), fucoidan crude extract (WH), >300 kDa fraction (300k) and <10 kDa fraction (10k) were compared in terms of chemical composition and antioxidant capacity. Based on Fourier transform infrared spectroscopy (FT-IR) analysis, Fstd, WH, and 300k all showed strong bands around 830 cm−1, corresponding to the sulfate substituent in the molecule. The results showed that compared with WH and 300 k, the degree of sulfation at 10k was the lowest. From Nuclear magnetic resonance spectroscopy (NMR) result, the four fucoidan samples all contain α-L-fucose. The primary antioxidant ability of the 10k is significantly higher than that of the 300k, WH, and Fstd, but the secondary antioxidant capabilities of the 10k and 300k were similar, and both were higher than that of the butylated hydroxyanisole (BHA). The ferric reducing antioxidant ability was higher in the 300k and WH fractions. This demonstrates that fucoidan extracted from U. pinnatifida grown in Weihai, China should be a useful nutraceutical resource.
dc.publisherFrontiers Mediaen_NZ
dc.relation.urihttps://www.frontiersin.org/articles/10.3389/fnut.2021.636930/full
dc.rightsCopyright © 2021 Yu, Li, Wu, Yang, Yang, Zhu, Liu, Tang, Nie, Hassouna, White, Zhao and Lu. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
dc.subjectFucoidan; Molecular weight; Antioxidant; Fraction; Chemical composition; Nutraceutical
dc.titleFucoidan Extracted From Sporophyll of Undaria Pinnatifida Grown in Weihai, China – Chemical Composition and Comparison of Antioxidant Activity of Different Molecular Weight Fractionsen_NZ
dc.typeJournal Article
dc.rights.accessrightsOpenAccessen_NZ
dc.identifier.doi10.3389/fnut.2021.636930en_NZ
aut.relation.articlenumber636930en_NZ
aut.relation.volume8en_NZ
pubs.elements-id431609
aut.relation.journalFrontiers in Nutritionen_NZ


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