School of Interprofessional Health Studies: Recent submissions
Now showing items 21-40 of 72
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Cytotoxicity of Extracts From New Zealand Surf Clams Against Organ Cancer Cell Lines
(MDPI, 2019)In this study, we examined the cytotoxic effects of four fractions from three species of New Zealand (NZ) surf clam on four common organ cancer cells. In most cases, a dose- and time-dependent inhibition on the proliferation ... -
Carbon-carbon Double Bond and Resorcinol in Resveratrol and Its Analogues: What Is the Characteristic Structure in Quenching Singlet Oxygen?
(MDPI AG, 2019)Stilbenes, particularly resveratrol and resveratrol dimers, could effectively quench singlet oxygen (1O2). It was reported that both resorcinol and carbon-carbon double bond quenching 1O2 can participate in the mechanism. ... -
Effect of Overexpression of LPAAT and GPD1 on Lipid Synthesis and Composition in Green Microalga Chlamydomonas Reinhardtii
(Springer Nature, 2018)Biodiesel is an alternative energy source which has attracted increasing attention lately. Although algae-based biodiesel production has many benefits, it is still far from industrial application. Research suggests that ... -
Preparation, Characterization, and Immuno-enhancing Activity of Polysaccharides From Glycyrrhiza Uralensis
(MDPI AG, 2020)Glycyrrhiza uralensis is a Chinese herbal medicine with various bioactivities. Three fractions (GUPS-I, GUPS-II and GUPS-III) of G. uralensis polysaccharides (GUPS) were obtained with molecular weights of 1.06, 29.1, and ... -
Can the Molar Insulin: C-Peptide Ratio Be Used to Predict Hyperinsulinaemia?
(MDPI, 2020)Hyperinsulinaemia is the precursor to numerous metabolic disorders. Early diagnosis and intervention could improve population health. Diagnosing hyperinsulinaemia is problematic because insulin has a very short half-life ... -
High-intensity Interval Training: A Review of Its Impact on Glucose Control and Cardiometabolic Health
(Springer Nature, 2017)Exercise plays a central role in the management and treatment of common metabolic diseases, but modern society presents many barriers to exercise. Over the past decade there has been considerable interest surrounding ... -
Leptin: A Pleitropic Factor in Physiology
Leptin, a 16 kDa protein and a product of the ob/ob gene, has a tertiary structure similar to that of a cytokine. It is primarily secreted by white adipose tissue and its levels in the blood correlate positively with ... -
Transport-mediated Oxaliplatin Resistance Associated With Endogenous Overexpression of MRP2 in Caco-2 and PANC-1 Cells
(MDPI AG, 2019)Our recent publications showed that multidrug resistance protein 2 (MRP2, encoded by the ABCC2 gene) conferred oxaliplatin resistance in human liver cancer HepG2 cells. However, the contribution of MRP2 to oxaliplatin ... -
Identification of MRP2 As a Targetable Factor Limiting Oxaliplatin Accumulation and Response in Gastrointestinal Cancer
(Nature Publishing Group, 2019)Oxaliplatin is important for the clinical treatment of colorectal cancer and other gastrointestinal malignancies, but tumour resistance is limiting. Several oxaliplatin transporters were previously identified but their ... -
Interventions to Prevent Women Developing Gestational Diabetes Mellitus: An Overview of Cochrane Reviews
(Cochrane Collaboration, 2019)This is a protocol for a Cochrane Review (Overview). The objectives are as follows: To summarise the evidence from Cochrane systematic reviews regarding the effects of interventions to prevent women developing gestational ... -
Through Pacific/Pasifika Lens to Understand Students Experiences to Promote Success Within New Zealand Tertiary Environment
(David Publishing, 2017)Traditionally, education environments are Eurocentric. They have reinforced “pedagogy of the oppressed” where Western knowledge is reflected in the university curriculum and ways of learning and teaching. Factors influencing ... -
Repeatability Characteristics of Insulin Response Patterns and Measures of Insulin Resistance
(AOSIS, 2019)Background: Hyperinsulinaemia is emerging as an independent risk factor for metabolic disease, but diagnostic measures are limited. It is plausible that insulin resistance measures, such as homeostatic model assessment ... -
Determining a Diagnostic Algorithm for Hyperinsulinaemia
Background: Ascertaining Kraft dynamic insulin response patterns following a 3-h 100 g oral glucose tolerance test seems to be the most reliable method for diagnosing hyperinsulinaemia. However, this test may be too ... -
Selenium and Thyroid Health in NZ European Women
(Open Access Text (OAT), 2017)The primary aim of the study was to determine differences in the hormonal status (TSH, T3, and T4) between healthy participants and participants with Hashimoto’s thyroiditis. The secondary aim of the study was to assess ... -
Gestational Diabetes in New Zealand Ethnic Groups
(Open Access Text (OAT), 2016)In New Zealand the rise in gestational diabetes mellitus (GDM) prevalence reflects the current patterns of increasing obesity and diabetes. Approximately 61,000 women give birth in New Zealand every year, and about 4.9% ... -
Using Value to Assess Improvement in Healthcare; But What Counts As ‘Value’?
(Chartered Accountants (CA) Australia and New Zealand, 2016)We contribute to the literature by advancing the debate on valuing healthcare and its relevance to assessing improvement. A systematic literature review includes academic papers and reported case-based information. We ... -
The Influence of Stigma on Provision of HIV Pharmaceutical Care in New Zealand
(AUT University, 2018)With access to anti-retroviral therapy, HIV is now managed as a chronic condition, with life-expectancy similar to the general population and the possibility of achieving undetectable viral levels. -
Researching Relational Practice Using the Voice Centered Relational Approach
(The Tao Institute, 2016)The Voice Centered Relational Approach is a qualitative methodology which focuses on the voices (the stories and perspectives) within participant narratives. The theoretical framework underpinning this methodology is ... -
Fucoidan Extracted From Undaria Pinnatifida: Source for Nutraceuticals/Functional Foods
(MDPI, 2018)The importance of fucoidan as a functional ingredient in food, health products, and pharmaceutics is well-recognized due to its beneficial biological effects. Fucoidan is usually extracted from brown seaweeds, including ... -
The Effects of Synthetically Modified Natural Compounds on ABC Transporters
(MDPI, 2018)Multidrug resistance (MDR) is a major hurdle which must be overcome to effectively treat cancer. ATP-binding cassette transporters (ABC transporters) play pivotal roles in drug absorption and disposition, and overexpression ...