Browsing School of Interprofessional Health Studies by Author "Lu, J"

Carbon-carbon Double Bond and Resorcinol in Resveratrol and Its Analogues: What Is the Characteristic Structure in Quenching Singlet Oxygen?

Kong, Q; Ren, X; Qi, J; Yu, J; Lu, J; Wang, S (MDPI AG, 2019)

Stilbenes, particularly resveratrol and resveratrol dimers, could effectively quench singlet oxygen (1O2). It was reported that both resorcinol and carbon-carbon double bond quenching 1O2 can participate in the mechanism. ...

Combining Multiple Serum Biomarkers in Tumor Diagnosis: A Clinical Assessment

Li, X; Lu, J; Ren, H; Chen, T; Gao, L; Di, L; Song, Z; et al (Spandidos Publications, 2013)

The present study aimed to assess the diagnostic/ prognostic value of various clinical tumor markers, including carcinoembryonic antigen (CEA), neuron-specific enolase (NSE), cytokeratin 19 (CYFRA21-1), α-fetoprotein (AFP), ...

Covalently Immobilized Battacin Lipopeptide Gels With Activity Against Bacterial Biofilms

De Zoysa, GH; Wang, K; Lu, J; Hemar, Y; Sarojini, V (MDPI AG, 2020)

Novel antibiotic treatments are in increasing demand to tackle life-threatening infections from bacterial pathogens. In this study, we report the use of a potent battacin lipopeptide as an antimicrobial gel to inhibit ...

Cytotoxicity of Extracts From New Zealand Surf Clams Against Organ Cancer Cell Lines

Odeleye, T; White, WL; Lu, J (MDPI, 2019)

In this study, we examined the cytotoxic effects of four fractions from three species of New Zealand (NZ) surf clam on four common organ cancer cells. In most cases, a dose- and time-dependent inhibition on the proliferation ...

Effect of Lactobacillus Rhamnosus Probiotic in Early Pregnancy on Plasma Conjugated Bile Acids in a Randomised Controlled Trial

Chen, Y; Lu, J; Wickens, K; Stanley, T; Maude, R; Stone, P; Barthow, C; Crane, J; Mitchell, EA; Merien, F; Murphy, R (MDPI AG, 2021)

We have previously shown that probiotic supplementation with Lactobacillus rhamnosus HN001 (HN001) led to a reduced incidence of gestational diabetes mellitus (GDM). Here we investigate whether HN001 supplementation resulted ...

Effect of Overexpression of LPAAT and GPD1 on Lipid Synthesis and Composition in Green Microalga Chlamydomonas Reinhardtii

Wang, C; Li, Y; Lu, J; Deng, X; Li, H; Hu, Z (Springer Nature, 2018)

Biodiesel is an alternative energy source which has attracted increasing attention lately. Although algae-based biodiesel production has many benefits, it is still far from industrial application. Research suggests that ...

Effects of Different Doses of Eucalyptus Oil From Eucalyptus Globulus Labill on Respiratory Tract Immunity and Immune Function in Healthy Rats

Shao, J; Yin, Z; Wang, Y; Yang, Y; Tang, Q; Zhang, M; Jiao, J; Liu, C; Yang, M; Zhen, L; Hassouna, A; White, WL; Lu, J (Frontiers Media, 2020)

Eucalyptol (1,8-cineole), the major constituent of eucalyptus oil (EO), was used in traditional medicine as a remedy for colds and bronchitis. This study aimed at clarifying the effect of eucalyptol on respiratory immune ...

Engineering a Novel Antibody-peptide Bispecific Fusion Protein Against MERS-CoV

Wang, L; Xu, J; Kong, Y; Liang, R; Li, W; Li, J; Lu, J; Dimitrov, DS; Yu, F; Wu, Y; Ying, T (MDPI AG, 2019)

In recent years, tremendous efforts have been made in the engineering of bispecific or multi-specific antibody-based therapeutics by combining two or more functional antigen-recognizing elements into a single construct. ...

Estimating Cyanobacteria Community Dynamics and Its Relationship With Environmental Factors

Luo, W; Chen, H; Lei, A; Lu, J; Hu, Z (MDPI, 2014)

The cyanobacteria community dynamics in two eutrophic freshwater bodies (Tiegang Reservoir and Shiyan Reservoir) was studied with both a traditional microscopic counting method and a PCR-DGGE genotyping method. Results ...

Evaluation of Ethnic Variations in Visceral, Subcutaneous, Intra-pancreatic, and Intra-hepatic Fat Depositions by Magnetic Resonance Imaging Among New Zealanders

Yang, JZ; Dokpuang, D; Nemati, R; He, KH; Zheng, AB; Petrov, MS; Lu, J (MDPI, 2020)

Anthropometric indices, such as body mass index (BMI), waist circumference (WC), and waist to height ratio (WHtR), have limitations in accurately predicting the pathophysiology of diabetes mellitus, cardiovascular diseases, ...

Extracts From New Zealand Undaria Pinnatifida Containing Fucoxanthin As Potential Functional Biomaterials Against Cancer in Vitro

Wang, SK; Li, Y; White, WL; Lu, J (MDPI, 2014)

This study tested extracts from New Zealand seaweed Undaria pinnatifida containing fucoxanthin, in parallel with pure fucoxanthin, in nine human cancer cell lines, for anticancer activity. Growth inhibition effects of ...

Fucoidan Extracted From Undaria Pinnatifida: Source for Nutraceuticals/Functional Foods

Zhao, Y; Zheng, Y; Wang, J; Ma, S; Yu, Y; White, WL; Yang, S; Yang, F; Lu, J (MDPI, 2018)

The importance of fucoidan as a functional ingredient in food, health products, and pharmaceutics is well-recognized due to its beneficial biological effects. Fucoidan is usually extracted from brown seaweeds, including ...

Identification of MRP2 As a Targetable Factor Limiting Oxaliplatin Accumulation and Response in Gastrointestinal Cancer

Myint, K; Biswas, R; Li, Y; Jong, N; Jamieson, S; Liu, J; Han, C; Squire, C; Merien, F; Lu, J; Nakanishi, T; Tamai, I; McKeage, M (Nature Publishing Group, 2019)

Oxaliplatin is important for the clinical treatment of colorectal cancer and other gastrointestinal malignancies, but tumour resistance is limiting. Several oxaliplatin transporters were previously identified but their ...

The Impact of Curcumin-graphene Based Nanoformulation on Cellular Interaction and Redox-activated Apoptosis: An in Vitro Colon Cancer Study

Al-Ani, LA; Kadir, FA; Hashim, NM; Julkapli, NM; Seyfoddin, A; Lu, J; AlSaadi, MA; Yehye, WA (Elsevier, 2020)

Natural plants derivatives have gained enormous merits in cancer therapy applications upon formulation with nanomaterials. Curcumin, as a popular research focus has acquired such improvements surpassing its disadvantageous ...

Mechanism of Resveratrol Dimers Isolated from Grape Inhibiting ¹O₂ Induced DNA Damage by UHPLC-QTOF-MS² and UHPLC-QQQ-MS² Analyses

Kong, Q; Zeng, Q; Yu, J; Xiao, H; Lu, J; Ren, X (MDPI AG, 2021)

Resveratrol dimers have been extensively reported on due to their antioxidative activity. Previous studies revealed that resveratrol dimer has been shown to selectively quench singlet oxygen (1O2), and could protect DNA ...

Metformin in gestational diabetes: The offspring follow-up (MiG TOFU): Body composition and metabolic outcomes at 7-9 years of age

Rowan, JA; Rush, EC; Plank, LD; Lu, J; Obolonkin, V; Coat, S; Hague, WM (BMJ Publishing, 2018)

Objective: To compare body composition and metabolic outcomes at 7-9 years in offspring of women with gestational diabetes (GDM) randomized to metformin (±insulin) or insulin treatment during pregnancy. Research design and ...