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Institute Director: Professor Valery Feigin

Deputy Director: Associate Professor Alice Theadom


The National Institute for Stroke and Applied Neurosciences (NISAN) conducts epidemiological studies and clinical trials to improve health and outcomes in people with major neurological disorders. Current research programmes focus on:
  • Stroke
  • Traumatic brain injury
  • Neuromuscular disorders
Research with this aim is unique in New Zealand and NISAN is a hub for information sharing and developing a cohesive network between existing research and clinical groups with interests in:
  • Neuroepidemiology
  • Public health
  • Neurorehabilitation
  • Neuropsychology
  • Biostatistics

  • Any use you make of these works must be for research or private study purposes only, and you may not make them available to any other person.
  • Authors control the copyright of their works. You will recognise the author’s right to be identified as the author of the work, and due acknowledgement will be made to the author where appropriate.
  • You will obtain the author’s permission before publishing any material from the work.

Recently Added

  • Subnational Mapping of HIV Incidence and Mortality Among Individuals Aged 15–49 Years in Sub-Saharan Africa, 2000–18: A Modelling Study

    Sartorius, B; VanderHeide, JD; Yang, M; Goosmann, EA; Hon, J; Haeuser, E; Cork, MA; Perkins, S; Jahagirdar, D; Schaeffer, LE; Serfes, AL; LeGrand, KE; Abbastabar, H; Abebo, ZH; Abosetugn, AE; Abu-Gharbieh, E; Accrombessi, MMK; Adebayo, OM; Adegbosin, AE; Adekanmbi, V; Adetokunboh, OO; Adeyinka, DA; Ahinkorah, BO; Ahmadi, K; Ahmed, MB; Akalu, Y; Akinyemi, OO; Akinyemi, RO; Aklilu, A; Akunna, CJ; Alahdab, F; Al-Aly, Z; Alam, N; Alamneh, AA; Alanzi, TM; Alemu, BW; Alhassan, RK; Ali, T; Alipour, V; Amini, S; Ancuceanu, R; Ansari, F; Anteneh, ZA; Anvari, D; Anwer, R; Appiah, SCY; Arabloo, J; Asemahagn, MA; Asghari Jafarabadi, M; Asmare, WN; Atnafu, DD; Atout, MMDW; Atreya, A; Ausloos, M; Awedew, AF; Ayala Quintanilla, BP; Ayanore, MA; Aynalem, YA; Ayza, MA; Azari, S; Azene, ZN; Babar, ZUD; Baig, AA; Balakrishnan, S; Banach, M; Bärnighausen, TW; Basu, S; Bayati, M; Bedi, N; Bekuma, TT; Bezabhe, WMM; Bhagavathula, AS; Bhardwaj, P; Bhattacharyya, K; Bhutta, ZA; Bibi, S; Bikbov, B; Birhan, TA; Bitew, ZW; Bockarie, MJ; Boloor, A; Brady, OJ; Bragazzi, NL; Briko, AN; Briko, NI; Burugina Nagaraja, S; Butt, ZA; Cárdenas, R; Carvalho, F; Charan, J; Chatterjee, S; Chattu, SK; Chattu, VK; Chowdhury, MAK; Chu, DT; Cook, AJ; Cormier, NM; Cowden, RG; Culquichicon, C; Dagnew, B (Elsevier, 2021)
    Background: High-resolution estimates of HIV burden across space and time provide an important tool for tracking and monitoring the progress of prevention and control efforts and assist with improving the precision and ...
  • Living with Dementia in Aotearoa (LiDiA): A Cross-sectional Feasibility Study Protocol for a Multiethnic Dementia Prevalence Study in Aotearoa/New Zealand

    Martinez-Ruiz, A; Yates, S; Cheung, G; Dudley, M; Krishnamurthi, R; Fa'alau, F; Roberts, M; Taufa, S; Fa'alili-Fidow, J; Rivera-Rodriguez, C; Kautoke, S; Ma'u, E; Kerse, N; Cullum, S (2021)
    INTRODUCTION: Aotearoa/New Zealand (NZ) is officially recognised as a bicultural country composed of Māori and non-Māori. Recent estimations have projected a threefold increase in dementia prevalence in NZ by 2050, with ...
  • The Incidence of Stroke in Indigenous Populations of Countries With a Very High Human Development Index: A Systematic Review Protocol

    Babalanski, AH; Dos Santos, A; Woods, JA; Thrift, AG; Kleinig, TJ; Suchy-Dicey, A; Siri, SR; Boden-Albala, B; Krishnamurthi, R; Feigin, V; Buchwald, D; Ranta, A; Mienna, CS; Zavaleta, C; Churilov, L; Burchill, L; Zion, D; Longstreth Jr, WT; Tirschwell, DL; Anand, S; Parsons, MW; Brown, A; Warne, DK; Harwood, M; Katzenellenbogen, JM (Frontiers Media, 2021)
    Background and Aims: Despite known Indigenous health and socioeconomic disadvantage in countries with a Very High Human Development Index, data on the incidence of stroke in these populations are sparse. With oversight ...
  • Ambient Air Pollution Exposure Estimation for the Global Burden of Disease 2012

    Brauer, M; Feigin, V; et al (American Chemical Society (ACS), 2015)
    Exposure to ambient air pollution is a major risk factor for global disease. Assessment of the impacts of air pollution on population health and evaluation of trends relative to other major risk factors requires regularly ...
  • Prevalence of Muscular Dystrophies: A Systematic Literature Review

    Theadom, A; Rodrigues, M; Roxburgh, R; Balalla, S; Higgins, C; Bhattacharjee, R; Jones, K; Krishnamurthi, R; Feigin, V (Karger, 2014)
    Background: Determining the prevalence of neuromuscular disorders for the general population is important to identify the scope of burden on society and enable comparisons with other health conditions. This systematic ...
  • What Is the Best Mix of Population‐wide and High‐risk Targeted Strategies of Primary Stroke and Cardiovascular Disease Prevention?

    Feigin, VL; Brainin, M; Norrving, B; Gorelick, PB; Dichgans, M; Wang, W; Pandian, JD; Martins, SCO; Owolabi, MO; Wood, DA; Hankey, GJ (Wiley-Blackwell, 2020)
    No abstract.
  • Head Impact Exposure Comparison Between Male and Female Amateur Rugby League Participants Measured With an Instrumented Patch

    King, D; Hume, P; Cummins, C; Clark, T; Gissane, C; Hecimovich, M (Heighten Science, 2019)
    Background: Epidemiological studies report that females experience greater rates of concussion when compared with males. Biomechanical factors may result in greater post-impact head velocities and accelerations for a given ...
  • Burden of Neurodegenerative Diseases in the Eastern Mediterranean Region, 1990-2016: Findings From the Global Burden of Disease 2016 Study

    Fereshtehnejad, S-M; Vosoughi, K; Heydarpour, P; Sepanlou, SG; Farzadfar, F; Tehrani-Banihashemi, A; Malekzadeh, R; Sahraian, MA; Vollset, SE; Naghavi, M; Vos, T; Feigin, V; Murray, C; Mokdad, AH; Moradi-Lakeh, M (Wiley, 2019)
    BACKGROUND AND PURPOSE: The Eastern Mediterranean Region (EMR) is experiencing a demographic shift towards rapid ageing at a time of political unrest. We aimed to estimate the burden of neurodegenerative disorders, and its ...
  • The burden of headache disorders in the Eastern Mediterranean Region, 1990-2016: Findings from the Global Burden of Disease study 2016

    Vosoughi, K; Stovner, LJ; Steiner, TJ; Moradi-Lakeh, M; Fereshtehnejad, S-M; Farzadfar, F; Heydarpour, P; Malekzadeh, R; Naghavi, M; Sahraian, MA; Sepanlou, SG; Tehrani-Banihashemi, A; Majdzadeh, R; Feigin, VL; Vos, T; Mokdad, AH; Murray, CJL (Springer, 2019)
    OBJECTIVES: Using the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016. METHODS: We modelled headache ...
  • The Burden of Headache Disorders in the Eastern Mediterranean Region, 1990-2016: Findings From the Global Burden of Disease Study 2016

    Vosoughi, K; Stovner, LJ; Steiner, TJ; Moradi-Lakeh, M; Fereshtehnejad, S-M; Farzadfar, F; Heydarpour, P; Malekzadeh, R; Naghavi, M; Sahraian, MA; Sepanlou, SG; Tehrani-Banihashemi, A; Majdzadeh, R; Feigin, VL; Vos, T; Mokdad, AH; Murray, CJL (Springer, 2019)
    OBJECTIVES: Using the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016. METHODS: We modelled headache ...
  • Health Effects of Dietary Risks in 195 Countries, 1990–2017: A Systematic Analysis for the Global Burden of Disease Study 2017

    Feigin, V; GBD 2017 Diet Collaborators (Elsevier, 2019)
    Background Suboptimal diet is an important preventable risk factor for non-communicable diseases (NCDs); however, its impact on the burden of NCDs has not been systematically evaluated. This study aimed to evaluate the ...
  • Health effects of dietary risks in 195 countries, 1990–2017: A systematic analysis for the Global Burden of Disease Study 2017

    Ashkan, A; Patrick John, S; Kairsten A., F; Feigin, V; GBD 2017 Diet Collaborators (Elsevier, 2019)
  • A Systematic Review of the Worldwide Prevalence of Survivors of Poliomyelitis Reported in 31 Studies

    Jones, KM; Balalla, S; Theadom, A; Jackman, G; Feigin, VL (BMJ Publishing Group Ltd., 2017)
    Background Accurate prevalence figures estimating the number of survivors of poliomyelitis (disease causing acute flaccid paralysis) following poliovirus infection are not available. We aim to undertake a systematic review ...
  • Global, Regional, and National Burden of Neurological Disorders During 1990-2015: A Systematic Analysis for the Global Burden of Disease Study 2015

    Feigin, VL; Abajobir, AA; Abate, KH; Abd-Allah, F; Abdulle, AM; Abera, SF; Abyu, GY; Ahmed, MB; Aichour, AN; Aichour, I; Aichour, MTE; Akinyemi, RO; Alabed, S; Al-Raddadi, R; Alvis-Guzman, N; Amare, AT; Ansari, H; Anwari, P; Arnlov, J; Asayesh, H; Asgedom, SW; Atey, TM; Avila-Burgos, L; Avokpaho, EFGA; Azarpazhooh, MR; Barac, A; Barboza, M; Barker-Collo, SL; Baernighausen, T; Bedi, N; Beghi, E; Bennett, DA; Bensenor, IM; Berhane, A; Betsu, BD; Bhaumik, S; Birlik, SM; Biryukov, S; Boneya, DJ; Bulto, LN; Carabin, H; Casey, D; Castaneda-Orjuela, CA; Catala-Lopez, F; Chen, H; Chitheer, AA; Chowdhury, R; Christensen, H; Dandona, L; Dandona, R; deVeber, GA; Dharmaratne, SD; Do, HP; Dokova, K; Dorsey, ER; Ellenbogen, RG; Eskandarieh, S; Farvid, MS; Fereshtehnejad, S-M; Fischer, F; Foreman, KJ; Geleijnse, JM; Gillum, RF; Giussani, G; Goldberg, EM; Gona, PN; Goulart, AC; Gugnani, HC; Gupta, R; Gupta, R; Hachinski, V; Hamadeh, RR; Hambisa, M; Hankey, GJ; Hareri, HA; Havmoeller, R; Hay, SI; Heydarpour, P; Hotez, PJ; Jakovljevic, MMB; Javanbakht, M; Jeemon, P; Jonas, JB; Kalkonde, Y; Kandel, A; Karch, A; Kasaeian, A; Kastor, A; Keiyoro, PN; Khader, YS; Khalil, IA; Khan, EA; Khang, Y-H; Khoja, AT; Khubchandani, J; Kulkarni, C; Kim, D; Kim, YJ; Kivimaki, M; Kokubo, Y; Kosen, S; Kravchenko, M; Krishnamurthi, RV; Defo, BK; Kumar, GA; Kumar, R; Kyu, HH; Larsson, A; Lavados, PM; Li, Y; Liang, X; Liben, ML; Lo, WD; Logroscino, G; Lotufo, PA; Loy, CT; Mackay, MT; Abd El Razek, HM; Abd El Razek, MM; Majeed, A; Malekzadeh, R; Manhertz, T; Mantovani, LG; Massano, J; Mazidi, M; McAlinden, C; Mehata, S; Mehndiratta, MM; Memish, ZA; Mendoza, W; Mengistie, MA; Mensah, GA; Meretoja, A; Mezgebe, HB; Miller, TR; Mishra, SR; Ibrahim, NM; Mohammadi, A; Mohammed, KE; Mohammed, S; Mokdad, AH; Moradi-Lakeh, M; Velasquez, IM; Musa, KI; Naghavi, M; Ngunjiri, JW; Nguyen, CT; Nguyen, G; Nguyen, QL; Nguyen, TH; Nichols, E; Ningrum, DN; Nong, VM; Norrving, B; Noubiap, JJN; Ogbo, FA; Owolabi, MO; Pandian, JD; Parmar, PG; Pereira, DM; Petzold, M; Phillips, MR; Piradov, MA; Poulton, RG; Pourmalek, F; Qorbani, M; Rafay, A; Rahman, M; Rahman, MH; Rai, RK; Rajsic, S; Ranta, A; Rawaf, S; Renzaho, AMN; Rezai, MS; Roth, GA; Roshandel, G; Rubagotti, E; Sachdev, P; Safiri, S; Sahathevan, R; Sahraian, MA; Samy, AM; Santalucia, P; Santos, IS; Sartorius, B; Satpathy, M; Sawhney, M; Saylan, MI; Sepanlou, SG; Shaikh, MA; Shakir, R; Shamsizadeh, M; Sheth, KN; Shigematsu, M; Shoman, H; Silva, DA; Smith, M; Sobngwi, E; Sposato, LA; Stanaway, JD; Stein, DJ; Steiner, TJ; Stovner, LJ; Abdulkader, RS; Szoeke, CEI; Tabares-Seisdedos, R; Tanne, D; Theadom, AM; Thrift, AG; Tirschwell, DL; Topor-Madry, R; Tran, BX; Truelsen, T; Tuem, KB; Ukwaja, KN; Uthman, OA; Varakin, YY; Vasankari, T; Venketasubramanian, N; Vlassov, VV; Wadilo, F; Wakayo, T; Wallin, MT; Weiderpass, E; Westerman, R; Wijeratne, T; Wiysonge, CS; Woldu, MA; Wolfe, CDA; Xavier, D; Xu, G; Yano, Y; Yimam, HH; Yonemoto, N; Yu, C; Zaidi, Z; Zaki, MES; Zunt, JR; Murray, CJL; Vos, T; Disorders, GBDN (Elsevier, 2017)
    Background Comparable data on the global and country-specific burden of neurological disorders and their trends are crucial for health-care planning and resource allocation. The Global Burden of Diseases, Injuries, and ...
  • Global, Regional, and National Burden of Neurological Disorders, 1990-2016: A Systematic Analysis for the Global Burden of Disease study 2016

    Feigin, V; GBD 2016 Neurology Collaborators (Elsevier, 2019)
    Background Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is ...
  • Global, regional, and national burden of neurological disorders, 1990-2016: A systematic analysis for the Global Burden of Disease study 2016

    Feigin, V; Emma, N; Tahiya, A; Marlena S, B; GBD 2016 Neurology Collaborators (Elsevier, 2019)
  • Global, Regional, and National Burden of Brain and Other Cns Cancer, 1990-2016: A Systematic Analysis for the Global Burden of Disease Study 2016

    Feigin, V; GBD 2016 Brain and other CNS Cancer Collaborators (Elsevier, 2019)
    Background Brain and CNS cancers (collectively referred to as CNS cancers) are a source of mortality and morbidity for which diagnosis and treatment require extensive resource allocation and sophisticated diagnostic and ...
  • Global, regional, and national burden of brain and other CNS cancer, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016

    Patel, AP; Fisher, JL; Nichols, E; Feigin, V; GBD 2016 Brain and other CNS Cancer Collaborators (Elsevier, 2019)
  • Global, Regional, and National Burden of Epilepsy, 1990-2016: A Systematic Analysis for the Global Burden of Disease Study 2016

    Feigin, V; GBD 2016 Epilepsy Collaborators (Elsevier, 2019)
    Background Seizures and their consequences contribute to the burden of epilepsy because they can cause health loss (premature mortality and residual disability). Data on the burden of epilepsy are needed for health-care ...
  • Global, regional, and national burden of epilepsy, 1990-2016: A systematic analysis for the Global Burden of Disease Study 2016

    Beghi, E; Giussani, G; Nichols, E; Feigin, V; GBD 2016 Epilepsy Collaborators (Elsevier, 2019)

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