Non-invasive Biomarkers for Early Detection of Breast Cancer

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aut.relation.articlenumber2767en_NZ
aut.relation.issue10en_NZ
aut.relation.journalCancersen_NZ
aut.relation.volume12en_NZ
aut.researcherDrabsch, Julie
dc.contributor.authorLi, Jen_NZ
dc.contributor.authorGuan, Xen_NZ
dc.contributor.authorFan, Zen_NZ
dc.contributor.authorChing, L-Men_NZ
dc.contributor.authorLi, Yen_NZ
dc.contributor.authorWang, Xen_NZ
dc.contributor.authorCao, W-Men_NZ
dc.contributor.authorLiu, D-Xen_NZ
dc.date.accessioned2020-11-23T00:49:19Z
dc.date.available2020-11-23T00:49:19Z
dc.date.copyright2020en_NZ
dc.date.issued2020en_NZ
dc.description.abstractBreast cancer is the most common cancer in women worldwide. Accurate early diagnosis of breast cancer is critical in the management of the disease. Although mammogram screening has been widely used for breast cancer screening, high false-positive and false-negative rates and radiation from mammography have always been a concern. Over the last 20 years, the emergence of "omics" strategies has resulted in significant advances in the search for non-invasive biomarkers for breast cancer diagnosis at an early stage. Circulating carcinoma antigens, circulating tumor cells, circulating cell-free tumor nucleic acids (DNA or RNA), circulating microRNAs, and circulating extracellular vesicles in the peripheral blood, nipple aspirate fluid, sweat, urine, and tears, as well as volatile organic compounds in the breath, have emerged as potential non-invasive diagnostic biomarkers to supplement current clinical approaches to earlier detection of breast cancer. In this review, we summarize the current progress of research in these areas.en_NZ
dc.identifier.citationCancers, 12(10), 2767. doi:10.3390/cancers12102767
dc.identifier.doi10.3390/cancers12102767en_NZ
dc.identifier.issn2072-6694en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/13811
dc.languageengen_NZ
dc.publisherMDPI
dc.relation.urihttps://www.mdpi.com/2072-6694/12/10/2767
dc.rights© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
dc.rights.accessrightsOpenAccessen_NZ
dc.subjectBiomarkeren_NZ
dc.subjectBlooden_NZ
dc.subjectBody fluiden_NZ
dc.subjectBreast canceren_NZ
dc.subjectDetectionen_NZ
dc.subjectDiagnosisen_NZ
dc.titleNon-invasive Biomarkers for Early Detection of Breast Canceren_NZ
dc.typeJournal Article
pubs.elements-id392620
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Health & Environmental Science
pubs.organisational-data/AUT/PBRF
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences/HA Science 2018 PBRF
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences/HI Interprofessional 2018 PBRF
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