The Effectiveness of Naltrexone Combined With Current Smoking Cessation Medication to Attenuate Post Smoking Cessation Weight Gain: A Literature Review

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aut.relation.issue20en_NZ
aut.relation.journalJournal of Pharmaceutical Policy and Practiceen_NZ
aut.relation.volume10en_NZ
aut.researcherSeyfoddin, Ali
dc.contributor.authorRees, Ren_NZ
dc.contributor.authorSeyfoddin, Aen_NZ
dc.date.accessioned2017-10-25T00:50:18Z
dc.date.available2017-10-25T00:50:18Z
dc.date.copyright2017en_NZ
dc.date.issued2017en_NZ
dc.description.abstractBackground Smoking is the number one cause of preventable morbidity and mortality globally and although many countries have invested heavily in smoking cessation programs, 21% of the global population still smoke. Post cessation weight gain has been identified as a barrier to attempting cessation and is implicated in the high rates of relapse. Naltrexone has been touted as a possible solution to address post smoking cessation weight gain. Results The results from seven original studies assessing the effectiveness of naltrexone in combination with existing smoking cessation medications to attenuate post smoking cessation weight gain were obtained and critically reviewed. Five returned positive results and two returned results that were statistically insignificant. The positive results were seen more often in those identified as more likely to exhibit hedonic eating behaviour for example women and participants who were categorised as overweight or obese. Conclusion The evidence suggests further investigation in to a combination of naltrexone and approved smoking cessation medications is warranted and could provide a solution to attenuate post smoking cessation weight gain especially in women and those classified as overweight or obese. This may provide the tool required to remove a perceived barrier to smoking cessation and improve global statistics.
dc.identifier.citationJournal of pharmaceutical policy and practice, 10(1), 20.
dc.identifier.doi10.1186/s40545-017-0109-7en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/10910
dc.publisherBioMed Central
dc.relation.urihttps://joppp.biomedcentral.com/articles/10.1186/s40545-017-0109-7en_NZ
dc.rights© The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
dc.rights.accessrightsOpenAccessen_NZ
dc.subjectNaltrexone; Smoking cessation; Weight gain
dc.titleThe Effectiveness of Naltrexone Combined With Current Smoking Cessation Medication to Attenuate Post Smoking Cessation Weight Gain: A Literature Reviewen_NZ
dc.typeJournal Article
pubs.elements-id284262
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Health & Environmental Science
pubs.organisational-data/AUT/Health & Environmental Science/Interprofessional Health
pubs.organisational-data/AUT/PBRF
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences
pubs.organisational-data/AUT/PBRF/PBRF Health and Environmental Sciences/HI Interprofessional 2018 PBRF
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