Utilization of 3D Printing Technology to Facilitate and Standardize Soft Tissue Testing

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aut.relation.issue1en_NZ
aut.relation.journalScientific Reportsen_NZ
aut.relation.volume8en_NZ
aut.researcherRamezani, Maziar
dc.contributor.authorScholze, Men_NZ
dc.contributor.authorSingh, Aen_NZ
dc.contributor.authorLozano, PFen_NZ
dc.contributor.authorOndruschka, Ben_NZ
dc.contributor.authorRamezani, Men_NZ
dc.contributor.authorWerner, Men_NZ
dc.contributor.authorHammer, Nen_NZ
dc.date.accessioned2018-10-01T23:12:06Z
dc.date.available2018-10-01T23:12:06Z
dc.date.copyright2018-12-01en_NZ
dc.date.issued2018-12-01en_NZ
dc.description.abstractThree-dimensional (3D) printing has become broadly available and can be utilized to customize clamping mechanisms in biomechanical experiments. This report will describe our experience using 3D printed clamps to mount soft tissues from different anatomical regions. The feasibility and potential limitations of the technology will be discussed. Tissues were sourced in a fresh condition, including human skin, ligaments and tendons. Standardized clamps and fixtures were 3D printed and used to mount specimens. In quasi-static tensile tests combined with digital image correlation and fatigue trials we characterized the applicability of the clamping technique. Scanning electron microscopy was utilized to evaluate the specimens to assess the integrity of the extracellular matrix following the mechanical tests. 3D printed clamps showed no signs of clamping-related failure during the quasi-static tests, and intact extracellular matrix was found in the clamping area, at the transition clamping area and the central area from where the strain data was obtained. In the fatigue tests, material slippage was low, allowing for cyclic tests beyond 105cycles. Comparison to other clamping techniques yields that 3D printed clamps ease and expedite specimen handling, are highly adaptable to specimen geometries and ideal for high-standardization and high-throughput experiments in soft tissue biomechanics.en_NZ
dc.identifier.citationScientific reports, 8(1), 11340.
dc.identifier.doi10.1038/s41598-018-29583-4en_NZ
dc.identifier.issn2045-2322en_NZ
dc.identifier.urihttps://hdl.handle.net/10292/11844
dc.publisherSpringer Nature Ltd.
dc.relation.urihttps://www.nature.com/articles/s41598-018-29583-4
dc.rightsThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
dc.rights.accessrightsOpenAccessen_NZ
dc.titleUtilization of 3D Printing Technology to Facilitate and Standardize Soft Tissue Testingen_NZ
dc.typeJournal Article
pubs.elements-id341968
pubs.organisational-data/AUT
pubs.organisational-data/AUT/Design & Creative Technologies
pubs.organisational-data/AUT/Design & Creative Technologies/Engineering, Computer & Mathematical Sciences
pubs.organisational-data/AUT/PBRF
pubs.organisational-data/AUT/PBRF/PBRF Design and Creative Technologies
pubs.organisational-data/AUT/PBRF/PBRF Design and Creative Technologies/PBRF ECMS
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