Recent work examining entrepreneurial scientists demonstrate that different conceptualizations and types exist (Lam, 2010, Louis et al., 1989). The diversity of scientific types suggests that there are a range of adaptive and engagement strategies that scientists employ within these knowledge regimes (Bercovitz and Feldman, 2008, Lam, 2010). This study systematically examines how individual orientations of scientists are mediated by its institutional and organizational contexts and the management strategies of these organizations in response to the rhetoric of new public management for entrepreneurship and commercial outcomes (Cartner and Bollinger, 1997, Luke et al., 2008).