AUT LibraryAUT
View Item 
  •   Open Theses & Dissertations
  • Doctoral Theses
  • View Item
  •   Open Theses & Dissertations
  • Doctoral Theses
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Investigation Into Nasal Saline Irrigation Within a Healthy Human Nose

Salati, Hana
Restricted files

One or more files will be made publicly available from 2022-06-24.

Permanent link
http://hdl.handle.net/10292/12583
Metadata
Show full metadata
Abstract
Nasal saline irrigation is a therapy that bathes the nasal mucosa with a liquid saline solution to treat inflammatory nasal and paranasal disease or manage post nasal and sinus surgery recovery. Saline irrigation is thought to improve nasal airway surface liquid (ASL) hydration and mucociliary transport. Also, it has previously shown that mechanical factors, including cyclic pressure and wall shear stresses distribution, may positively influence mucociliary clearance.

A detailed saline flow analysis within the nasal cavities and maxillary sinuses during saline irrigation in various head positions and side directions, in the presence of a nasal cycle geometry, has not previously been investigated. Knowledge of the saline flow fields within the nasal cavities and maxillary sinuses during nasal saline irrigation is essential to an understanding of how different head positions and side directions affect the targeted delivery site, and whether the irrigant has the potential to stimulate the mucociliary functions at different regions of the nasal cavities and maxillary sinuses. In this thesis the distribution and pressure of the irrigant, and the mucosal wall shear stress in the human nasal cavities and maxillary sinuses, have been mapped during nasal saline irrigation using computational fluid dynamics (CFD) simulations in the presence of the nasal cycle at four different head positions: Mygind (lying with head back), 90° (tilting the head sideways at 90°), head back (head is oriented 45° upward from the ground), and head forward (head is inclined downwards at 45° to the ground).

Particle image velocimetry (PIV) measurements have been applied to confirm the validity of the numerical methodology used in this study. Close agreement was found between numerical and experimental results performed under identical conditions and geometries.

New findings of this study have shown that saline irrigation at different head positions and side directions results in different saline distribution and saline pressure and mucosal wall shear stress distribution.

The findings of this study will allow both clinicians and patients to make better-informed decisions on optimal irrigation techniques to better realise the full benefits of this form of treatment.
Keywords
Nasal cavity; Head positions; CFD; PIV; Maxillary Sinuses; Nasal saline irrigation; CRS; MRI; Nasal cycle
Date
2019
Item Type
Thesis
Supervisor(s)
White, David; Nates, Roy; Bartley, Jim
Degree Name
Doctor of Philosophy
Publisher
Auckland University of Technology

Contact Us
  • Admin

Hosted by Tuwhera, an initiative of the Auckland University of Technology Library

 

 

Browse

Open Theses & DissertationsTitlesAuthorsDateThesis SupervisorDoctoral ThesesTitlesAuthorsDateThesis Supervisor

Alternative metrics

 

Statistics

For this itemFor all Open Theses & Dissertations

Share

 
Follow @AUT_SC

Contact Us
  • Admin

Hosted by Tuwhera, an initiative of the Auckland University of Technology Library