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dc.identifier.citationThe Journal of Headache and Pain, (2019) 20:40.
dc.description.abstractOBJECTIVES: Using the findings of the Global Burden of Disease Study (GBD), we report the burden of primary headache disorders in the Eastern Mediterranean Region (EMR) from 1990 to 2016. METHODS: We modelled headache disorders using DisMod-MR 2.1 Bayesian meta-regression tool to ensure consistency between prevalence, incidence, and remission. Years lived with disability (YLDs) were calculated by multiplying prevalence and disability weight (DW) of migraine and tension-type headache (TTH). We assumed primary headache disorders as non-fatal, so their YLD is equal to disability-adjusted life years (DALYs). RESULTS: Migraine and TTH were the second and twentieth leading causes of YLDs in EMR. Between 1990 and 2016, the absolute YLD numbers of migraine and TTH increased from 2.3 million (95% uncertainty interval (UI): 1.5-3.2) to 4.7 million (95%UI: 3-6.5) and from 383 thousand (95%UI: 240-562) to 816 thousand (95%UI: 516-1221), respectively. During the same period, age-standardised YLD rates of migraine and TTH in EMR increased by 0.7% and 2.5%, respectively, in comparison to a small decrease in the global rates (0.2% decrease in migraine and TTH). The bulk of burden due to headache occurred in the 30-49 year age group, with a peak at ages 35-44 years. The age-standardised YLD rates of both headache disorders were higher in women with female to male ratio of 1.69 for migraine and 1.38 for TTH. All countries of the EMR except for Somalia and Djibouti had higher age-standardised YLD rates for migraine and TTH in compare to the global rates. Libya and Saudi Arabia had the highest increase in age-standardised YLD rates of migraine and TTH, respectively. CONCLUSION: The findings of this study show that primary headache disorders are a major and a growing cause of disability in EMR. Since 1990, burden of primary headache disorders has constantly been higher in EMR compared to rest of the world, which indicates that health systems in EMR must focus further on developing and implementing preventive and management strategies to control headache.en_NZ
dc.rightsThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
dc.subjectDisability-adjusted life years (DALYs)en_NZ
dc.subjectEastern Mediterranean region (EMR)en_NZ
dc.subjectGlobal burden of disease study (GBD)en_NZ
dc.subjectPrimary headacheen_NZ
dc.subjectTension-type headacheen_NZ
dc.subjectYears lived with disability (YLDs)en_NZ
dc.titleThe Burden of Headache Disorders in the Eastern Mediterranean Region, 1990-2016: Findings From the Global Burden of Disease Study 2016en_NZ
dc.typeJournal Article
dark.contributor.authorVosoughi, Ken_NZ
dark.contributor.authorStovner, LJen_NZ
dark.contributor.authorSteiner, TJen_NZ
dark.contributor.authorMoradi-Lakeh, Men_NZ
dark.contributor.authorFereshtehnejad, S-Men_NZ
dark.contributor.authorFarzadfar, Fen_NZ
dark.contributor.authorHeydarpour, Pen_NZ
dark.contributor.authorMalekzadeh, Ren_NZ
dark.contributor.authorNaghavi, Men_NZ
dark.contributor.authorSahraian, MAen_NZ
dark.contributor.authorSepanlou, SGen_NZ
dark.contributor.authorTehrani-Banihashemi, Aen_NZ
dark.contributor.authorMajdzadeh, Ren_NZ
dark.contributor.authorFeigin, VLen_NZ
dark.contributor.authorVos, Ten_NZ
dark.contributor.authorMokdad, AHen_NZ
dark.contributor.authorMurray, CJLen_NZ
aut.relation.journalJournal of Headache and Painen_NZ

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